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Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis
(Biomed Central Ltd, London, 2017)
Background: Idiopathic Pulmonary Fibrosis (IPF) is a lethal lung disease of unknown etiology. A major limitation in transcriptomic profiling of lung tissue in IPF has been a dependence on snap-frozen fresh tissues (FF). ...
Application of Next-Generation Sequencing Technology and Establishment of Biobanks
(Karger, Basel, 2018)
Institute of Molecular Genetics and Genetic Engineering has
become widely recognized as an expert centre for rare diseases
(RD). It is the first institution is Serbia that applied NGS methodology in research and diagnostics ...
Virulence-related Mycobacterium avium subsp hominissuis MAV-2928 gene is associated with vacuole remodeling in macrophages
(BMC, 2010)
Background: Mycobacterium avium subsp hominissuis (previously Mycobacterium avium subsp avium) is an environmental organism associated with opportunistic infections in humans. Mycobacterium hominissuis infects and replicates ...
Emergence of VIM-2 metallo-beta-lactamase-producing Pseudomonas aeruginosa isolates in a paediatric hospital in Serbia
(Soc General Microbiology, Reading, 2011)
Molecular detection and surveillance of the
resistance genes harboured by
Pseudomonas aeruginosa are becoming
increasingly important in assessing and
controlling spread and colonization in
hospitals, and in guiding ...
In vitro and in vivo antagonistic activity of new probiotic culture against Clostridium difficile and Clostridium perfringens
(BMC, London, 2017)
Background: Genus Clostridium accompanies more than 200 known species and at least 30 among them are associated with human and animal diseases. At the moment, the treatment of clostridial infections is based on use of ...
Excited-State Hydroxide Ion Release From a Series of Acridinol Photobases
(Amer Chemical Soc, Washington, 2017)
The excited-state heterolysis of acridinol-based derivatives leads to the release of the OH- ion and the formation of the corresponding acridinium cations. To evaluate the parameters that control the reaction barriers, the ...
Frequencies of EGFR single nucleotide polymorphisms in non-small cell lung cancer patients and healthy individuals in the Republic of Serbia: a preliminary study
(Sage Publications Ltd, London, 2016)
The purpose of this study was to determine the frequencies of EGFR -216G gt T, -191C gt A, and 181946C gt T in Serbian non-small cell lung cancer (NSCLC) patients, as well as to compare it with healthy individuals, ...
Acinetobacter spp. porin Omp33-36: Classification and transcriptional response to carbapenems and host cells
(Public Library Science, San Francisco, 2018)
Acinetobacter baumannii has been recognized as one of the most challeging pathogens in clinical settings worldwide. Outer membrane porins play a significant role in Acinetobacter antibiotic resistance and virulence. A. ...
High yield preparation of genomic DNA from Streptomyces
(Eaton Publishing Co, Natick, 2003)
Cloning and expression of a novel lactococcal aggregation factor from Lactococcus lactis subsp lactis BGKP1
(Biomed Central Ltd, London, 2011)
Background: Aggregation may play a main role in the adhesion of bacteria to the gastrointestinal epithelium and their colonization ability, as well as in probiotic effects through co-aggregation with intestinal pathogens ...