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Late-stage diversification of bacterial natural products through biocatalysis
(Frontiers, 2024)
Bacterial natural products (BNPs) have been and still are very important sources of leads for drug development and chemical novelty. The possibility to perform late-stage diversification of these biomolecules is an attractive ...
Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation
(Elsevier Science Bv, Amsterdam, 2017)
The phage shock protein (Psp) response maintains integrity of the inner membrane (IM) in response to extracytoplasmic stress conditions and is widely distributed amongst enterobacteria. Its central component PspA, a member ...
Microbial Production of Violacein and Process Optimization for Dyeing Polyamide Fabrics With Acquired Antimicrobial Properties
(Frontiers Media Sa, Lausanne, 2018)
In the present study, crude bacterial extract containing violacein is investigated for the preparation of antimicrobial polyamide fabrics. The optimal culture conditions of Janthinobacterium lividum (JL) for maximum biomass ...
Identification and validation of differentially expressed transcripts by RNA-sequencing of formalin-fixed, paraffin-embedded (FFPE) lung tissue from patients with Idiopathic Pulmonary Fibrosis
(Biomed Central Ltd, London, 2017)
Background: Idiopathic Pulmonary Fibrosis (IPF) is a lethal lung disease of unknown etiology. A major limitation in transcriptomic profiling of lung tissue in IPF has been a dependence on snap-frozen fresh tissues (FF). ...
Chemical composition and antiproliferative potential of dried wild apple and pear tea before and after in vitro simulated digestion
(Srpsko hemijsko društvo, Beograd, 2018)
Decoctions obtained from dried apple and pear fruits were subjected to in vitro digestion in the presence of a food matrix in order to determine changes in the polyphenol content and antiproliferative activity. The total ...
Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves
(Srpsko hemijsko društvo, Beograd, 2018)
The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ...
Root malate efflux and expression of TaALMT1 in Serbian winter wheat cultivars differing in Al tolerance
(Sociedad Chilena de la Ciencia del Suelo, 2018)
Aluminium (Al) toxicity in acid soils is a global problem. Here, we investigated Al tolerance in high yielding winter wheat (Triticum aestivum L.) cultivars bred in Serbia. The common relative mot length (RRL) test for Al ...
Application of Next-Generation Sequencing Technology and Establishment of Biobanks
(Karger, Basel, 2018)
Institute of Molecular Genetics and Genetic Engineering has
become widely recognized as an expert centre for rare diseases
(RD). It is the first institution is Serbia that applied NGS methodology in research and diagnostics ...
Precision medicine and COVID-19: Importance of host genome profiling
(Institute of Molecular Genetics and Genetic Engineering (IMGGE), University of Belgrade, 2023)
Introduction: The clinical picture and the course of the disease in COVID-19 patients, caused by coronavirus SARS-CoV-2, vary from asymptomatic to fatal outcome. As the same agent cause the disease, the
individual genomic ...
Nuclear extract from REL cells contains GATA-1 transcription factor
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 1996)
Preparation of nuclear extracts from different tissues may provide the proteins that regulate gene expression in those tissues. REL (rat erythroleukemia) cells represent a permanent erythroid cell line. They are the most ...