TY  - JOUR
AU  - Araujo, Jeovan A.
AU  - Taxeidis, George
AU  - Pereira, Everton H.
AU  - Azeem, Muhammad
AU  - Pantelić, Brana
AU  - Jeremić, Sanja
AU  - Ponjavić, Marijana
AU  - Chen, Yuanyuan
AU  - Mojicević, Marija
AU  - Nikodinović-Runić, Jasmina
AU  - Topakas, Evangelos
AU  - Brennan Fournet, Margaret
PY  - 2024
UR  - https://www.sciencedirect.com/science/article/pii/S0959652624004724
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2315
AB  - Ubiquitous post-consumer plastic waste is often physically mixed combining recalcitrant petroleum-based plastics with bioplastics, forming (petro-bio)plastic streams. Finding appropriate end-of-life (EoL) strategies for mixed (petro-bio)plastic waste is highly pertinent in achieving environmental protection, sustainability for plastic value chain industries including recyclers and government policy makers worldwide. The presence of bioplastic mixed in with polyethylene terephthalate (PET) or other petroleum-based plastic streams poses a substantial drawback to mechanical recycling and strongly impedes the development of sustainable EoL routes. Here, we present a model system for the sustainable management of mixed (petro-bio)plastic waste, demonstrating a biotechnological route through synergy-promoted enzymatic degradation of PET–representing petrochemical polyester plastic–mixed with thermoplastic starch (TPS)–as a model bioplastic. Leaf-branch compost cutinase (LCCICCG) and commercial amylase (AMY) deliver effective depolymerization of this mixed (petro-bio)plastic material, with subsequent bio-upcycling of the mixed waste stream into bacterial nanocellulose (BNC) by Komagataeibacter medellinensis. Compared to LCCICCG and AMY, the LCCICCG/AMY combined treatment synergistically produced a 2.6- and 4.4-fold increase in enzymatic decomposition at 70 °C in four days, respectively, yielding sugars and terephthalic acid (TPA) as the main depolymerization building blocks. Bio-upcycling of post-enzymatic degradation hydrolysates resulted in a high BNC yield of 3 g L−1 after 10 days. This work paves the way for sustainable management routes for challenging mixed recalcitrant plastic and bioplastic waste and prepares opportunities for its participation in the circular production of sustainable eco-polymers.
PB  - Elsevier
T2  - Journal of Cleaner Production
T1  - Biotechnological model for ubiquitous mixed petroleum- and bio-based plastics degradation and upcycling into bacterial nanocellulose
SP  - 141025
DO  - 10.1016/j.jclepro.2024.141025
ER  - 

@article{
author = "Araujo, Jeovan A. and Taxeidis, George and Pereira, Everton H. and Azeem, Muhammad and Pantelić, Brana and Jeremić, Sanja and Ponjavić, Marijana and Chen, Yuanyuan and Mojicević, Marija and Nikodinović-Runić, Jasmina and Topakas, Evangelos and Brennan Fournet, Margaret",
year = "2024",
abstract = "Ubiquitous post-consumer plastic waste is often physically mixed combining recalcitrant petroleum-based plastics with bioplastics, forming (petro-bio)plastic streams. Finding appropriate end-of-life (EoL) strategies for mixed (petro-bio)plastic waste is highly pertinent in achieving environmental protection, sustainability for plastic value chain industries including recyclers and government policy makers worldwide. The presence of bioplastic mixed in with polyethylene terephthalate (PET) or other petroleum-based plastic streams poses a substantial drawback to mechanical recycling and strongly impedes the development of sustainable EoL routes. Here, we present a model system for the sustainable management of mixed (petro-bio)plastic waste, demonstrating a biotechnological route through synergy-promoted enzymatic degradation of PET–representing petrochemical polyester plastic–mixed with thermoplastic starch (TPS)–as a model bioplastic. Leaf-branch compost cutinase (LCCICCG) and commercial amylase (AMY) deliver effective depolymerization of this mixed (petro-bio)plastic material, with subsequent bio-upcycling of the mixed waste stream into bacterial nanocellulose (BNC) by Komagataeibacter medellinensis. Compared to LCCICCG and AMY, the LCCICCG/AMY combined treatment synergistically produced a 2.6- and 4.4-fold increase in enzymatic decomposition at 70 °C in four days, respectively, yielding sugars and terephthalic acid (TPA) as the main depolymerization building blocks. Bio-upcycling of post-enzymatic degradation hydrolysates resulted in a high BNC yield of 3 g L−1 after 10 days. This work paves the way for sustainable management routes for challenging mixed recalcitrant plastic and bioplastic waste and prepares opportunities for its participation in the circular production of sustainable eco-polymers.",
publisher = "Elsevier",
journal = "Journal of Cleaner Production",
title = "Biotechnological model for ubiquitous mixed petroleum- and bio-based plastics degradation and upcycling into bacterial nanocellulose",
pages = "141025",
doi = "10.1016/j.jclepro.2024.141025"
}

Araujo, J. A., Taxeidis, G., Pereira, E. H., Azeem, M., Pantelić, B., Jeremić, S., Ponjavić, M., Chen, Y., Mojicević, M., Nikodinović-Runić, J., Topakas, E.,& Brennan Fournet, M.. (2024). Biotechnological model for ubiquitous mixed petroleum- and bio-based plastics degradation and upcycling into bacterial nanocellulose. in Journal of Cleaner Production
Elsevier., 141025.
https://doi.org/10.1016/j.jclepro.2024.141025

Araujo JA, Taxeidis G, Pereira EH, Azeem M, Pantelić B, Jeremić S, Ponjavić M, Chen Y, Mojicević M, Nikodinović-Runić J, Topakas E, Brennan Fournet M. Biotechnological model for ubiquitous mixed petroleum- and bio-based plastics degradation and upcycling into bacterial nanocellulose. in Journal of Cleaner Production. 2024;:141025.
doi:10.1016/j.jclepro.2024.141025 .

Araujo, Jeovan A., Taxeidis, George, Pereira, Everton H., Azeem, Muhammad, Pantelić, Brana, Jeremić, Sanja, Ponjavić, Marijana, Chen, Yuanyuan, Mojicević, Marija, Nikodinović-Runić, Jasmina, Topakas, Evangelos, Brennan Fournet, Margaret, "Biotechnological model for ubiquitous mixed petroleum- and bio-based plastics degradation and upcycling into bacterial nanocellulose" in Journal of Cleaner Production (2024):141025,
https://doi.org/10.1016/j.jclepro.2024.141025 . .

TY  - CONF
AU  - Ponjavić, Marijana
AU  - Milovanović, Jelena
AU  - Nikodinović-Runić, Jasmina
AU  - Đurašković, Nikola
AU  - Tica, Nedeljko
AU  - Živković, Irena
PY  - 2024
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2334
AB  - In this paper, the biodegradability of three SferiCorn™
biocomposites was investigated. Corn stover prepared through eco-friendly
washing and grinding to short fibers was used as reinforcement. Three different
biopolymers, corn starch, alginate and poly(3-hydroxybutyrate-co-3-
hydroxyvalerate) (PHBV), were used as matrices. The biodegradability of
prepared composites was investigated in a simulated soil burial test and the
samples were characterized in terms of weight loss and morphological changes. It
was shown that biodegradability can be tuned by biopolymers used as matrices.
Changes in the surface morphology after biodegradation of tested samples were
confirmed using scanning electron microscopy (SEM).
PB  - Čačak : Faculty of Agronomy
C3  - 2nd International symposium on biotechnology
T1  - Biodegradability assessment of corn stover reinforced composite materials with different matrix
EP  - 261
SP  - 225
DO  - 10.46793/SBT29
ER  - 

@conference{
author = "Ponjavić, Marijana and Milovanović, Jelena and Nikodinović-Runić, Jasmina and Đurašković, Nikola and Tica, Nedeljko and Živković, Irena",
year = "2024",
abstract = "In this paper, the biodegradability of three SferiCorn™
biocomposites was investigated. Corn stover prepared through eco-friendly
washing and grinding to short fibers was used as reinforcement. Three different
biopolymers, corn starch, alginate and poly(3-hydroxybutyrate-co-3-
hydroxyvalerate) (PHBV), were used as matrices. The biodegradability of
prepared composites was investigated in a simulated soil burial test and the
samples were characterized in terms of weight loss and morphological changes. It
was shown that biodegradability can be tuned by biopolymers used as matrices.
Changes in the surface morphology after biodegradation of tested samples were
confirmed using scanning electron microscopy (SEM).",
publisher = "Čačak : Faculty of Agronomy",
journal = "2nd International symposium on biotechnology",
title = "Biodegradability assessment of corn stover reinforced composite materials with different matrix",
pages = "261-225",
doi = "10.46793/SBT29"
}

Ponjavić, M., Milovanović, J., Nikodinović-Runić, J., Đurašković, N., Tica, N.,& Živković, I.. (2024). Biodegradability assessment of corn stover reinforced composite materials with different matrix. in 2nd International symposium on biotechnology
Čačak : Faculty of Agronomy., 225-261.
https://doi.org/10.46793/SBT29

Ponjavić M, Milovanović J, Nikodinović-Runić J, Đurašković N, Tica N, Živković I. Biodegradability assessment of corn stover reinforced composite materials with different matrix. in 2nd International symposium on biotechnology. 2024;:225-261.
doi:10.46793/SBT29 .

Ponjavić, Marijana, Milovanović, Jelena, Nikodinović-Runić, Jasmina, Đurašković, Nikola, Tica, Nedeljko, Živković, Irena, "Biodegradability assessment of corn stover reinforced composite materials with different matrix" in 2nd International symposium on biotechnology (2024):225-261,
https://doi.org/10.46793/SBT29 . .

TY  - CONF
AU  - Milovanović, Jelena
AU  - Nenadović, Marija
AU  - Pantelić, Brana
AU  - Ponjavić,  Marijana
AU  - Sourkouni, Georgia
AU  - Kalogirou, Charalampia
AU  - Argirusis, Christos
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://esabweb.org/E_CONGRESS/Poster+Programme/Day/Online/All+day/Enhanced+enzymatic+depolymerization+of+polylactic+acid+%28PLA%29+through+plasma+pretreatment+and+subsequent+conversion+to+biopolymer.html
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2232
AB  - Polylactic acid (PLA) serves as a bio-based alternative to fossil-based single-use plastics, biodegrading at high temperatures (58°C) and humidity during industrial composting. Despite enzymes' ability to catalyze reactions at near-ambient temperatures, polymer rigidity can impede efficient depolymerization. To address these challenges, we conducted a study of enzymatic PLA degradation at 42°C combined with green plasma pretreatment to help disrupt the crystalline regions within the polymer. Here we report the effect of length of plasma pretreatment on the rate of PLA degradation by enzyme mix containing commercial enzymes with reported PLA degrading activity. Results indicate that a 5-minute plasma pretreatment significantly enhances enzymatic degradation, with a 16% weight loss achieved in 4 weeks—a two-fold increase compared to untreated PLA. Furthermore, we report the valorization of PLA into bacterial nanocellulose after enzymatic hydrolysis of the samples.
PB  - European Society of Applied Biocatalysis
C3  - ESAB E-Congress
T1  - Enhanced enzymatic depolymerization of polylactic acid (PLA) through plasma pretreatment and subsequent conversion to biopolymer
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2232
ER  - 

@conference{
author = "Milovanović, Jelena and Nenadović, Marija and Pantelić, Brana and Ponjavić,  Marijana and Sourkouni, Georgia and Kalogirou, Charalampia and Argirusis, Christos and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "Polylactic acid (PLA) serves as a bio-based alternative to fossil-based single-use plastics, biodegrading at high temperatures (58°C) and humidity during industrial composting. Despite enzymes' ability to catalyze reactions at near-ambient temperatures, polymer rigidity can impede efficient depolymerization. To address these challenges, we conducted a study of enzymatic PLA degradation at 42°C combined with green plasma pretreatment to help disrupt the crystalline regions within the polymer. Here we report the effect of length of plasma pretreatment on the rate of PLA degradation by enzyme mix containing commercial enzymes with reported PLA degrading activity. Results indicate that a 5-minute plasma pretreatment significantly enhances enzymatic degradation, with a 16% weight loss achieved in 4 weeks—a two-fold increase compared to untreated PLA. Furthermore, we report the valorization of PLA into bacterial nanocellulose after enzymatic hydrolysis of the samples.",
publisher = "European Society of Applied Biocatalysis",
journal = "ESAB E-Congress",
title = "Enhanced enzymatic depolymerization of polylactic acid (PLA) through plasma pretreatment and subsequent conversion to biopolymer",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2232"
}

Milovanović, J., Nenadović, M., Pantelić, B., Ponjavić, M., Sourkouni, G., Kalogirou, C., Argirusis, C.,& Nikodinović-Runić, J.. (2023). Enhanced enzymatic depolymerization of polylactic acid (PLA) through plasma pretreatment and subsequent conversion to biopolymer. in ESAB E-Congress
European Society of Applied Biocatalysis..
https://hdl.handle.net/21.15107/rcub_imagine_2232

Milovanović J, Nenadović M, Pantelić B, Ponjavić M, Sourkouni G, Kalogirou C, Argirusis C, Nikodinović-Runić J. Enhanced enzymatic depolymerization of polylactic acid (PLA) through plasma pretreatment and subsequent conversion to biopolymer. in ESAB E-Congress. 2023;.
https://hdl.handle.net/21.15107/rcub_imagine_2232 .

Milovanović, Jelena, Nenadović, Marija, Pantelić, Brana, Ponjavić,  Marijana, Sourkouni, Georgia, Kalogirou, Charalampia, Argirusis, Christos, Nikodinović-Runić, Jasmina, "Enhanced enzymatic depolymerization of polylactic acid (PLA) through plasma pretreatment and subsequent conversion to biopolymer" in ESAB E-Congress (2023),
https://hdl.handle.net/21.15107/rcub_imagine_2232 .

TY  - DATA
AU  - Solarz, Daria
AU  - Witko, Tomasz
AU  - Karcz, Robert
AU  - Malagurski, Ivana
AU  - Ponjavić, Marijana
AU  - Levic, Steva
AU  - Nešić, Aleksandra
AU  - Guzik, Maciej
AU  - Savić, Sanja
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://pubs.rsc.org/en/content/articlelanding/2023/ra/d3ra03021k
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2060
AB  - Polyhydroxyoctanoate, as a biocompatible and biodegradable biopolymer, represents an ideal candidate for biomedical applications. However, physical properties make it unsuitable for electrospinning, currently the most widely used technique for fabrication of fibrous scaffolds. To overcome this, it was blended with polylactic acid and polymer blend fibrous biomaterials were produced by electrospinning. The obtained PLA/PHO fibers were cylindrical, smaller in size, more hydrophilic and had a higher degree of biopolymer crystallinity and more favorable mechanical properties in comparison to the pure PLA sample. Cytotoxicity evaluation with human lung fibroblasts (MRC5 cells) combined with confocal microscopy were used to visualize mouse embryonic fibroblasts (MEF 3T3 cell line) migration and distribution showed that PLA/PHO samples support exceptional cell adhesion and viability, indicating excellent biocompatibility. The obtained results suggest that PLA/PHO fibrous biomaterials can be potentially used as biocompatible, biomimetic scaffolds for tissue engineering applications.
T2  - RSC Advances
T1  - Supplementary data for article: Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances, 13(34), 24112-24128. https://doi.org/10.1039/D3RA03021K
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2060
ER  - 

@misc{
author = "Solarz, Daria and Witko, Tomasz and Karcz, Robert and Malagurski, Ivana and Ponjavić, Marijana and Levic, Steva and Nešić, Aleksandra and Guzik, Maciej and Savić, Sanja and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "Polyhydroxyoctanoate, as a biocompatible and biodegradable biopolymer, represents an ideal candidate for biomedical applications. However, physical properties make it unsuitable for electrospinning, currently the most widely used technique for fabrication of fibrous scaffolds. To overcome this, it was blended with polylactic acid and polymer blend fibrous biomaterials were produced by electrospinning. The obtained PLA/PHO fibers were cylindrical, smaller in size, more hydrophilic and had a higher degree of biopolymer crystallinity and more favorable mechanical properties in comparison to the pure PLA sample. Cytotoxicity evaluation with human lung fibroblasts (MRC5 cells) combined with confocal microscopy were used to visualize mouse embryonic fibroblasts (MEF 3T3 cell line) migration and distribution showed that PLA/PHO samples support exceptional cell adhesion and viability, indicating excellent biocompatibility. The obtained results suggest that PLA/PHO fibrous biomaterials can be potentially used as biocompatible, biomimetic scaffolds for tissue engineering applications.",
journal = "RSC Advances",
title = "Supplementary data for article: Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances, 13(34), 24112-24128. https://doi.org/10.1039/D3RA03021K",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2060"
}

Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Supplementary data for article: Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances, 13(34), 24112-24128. https://doi.org/10.1039/D3RA03021K. in RSC Advances.
https://hdl.handle.net/21.15107/rcub_imagine_2060

Solarz D, Witko T, Karcz R, Malagurski I, Ponjavić M, Levic S, Nešić A, Guzik M, Savić S, Nikodinović-Runić J. Supplementary data for article: Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances, 13(34), 24112-24128. https://doi.org/10.1039/D3RA03021K. in RSC Advances. 2023;.
https://hdl.handle.net/21.15107/rcub_imagine_2060 .

Solarz, Daria, Witko, Tomasz, Karcz, Robert, Malagurski, Ivana, Ponjavić, Marijana, Levic, Steva, Nešić, Aleksandra, Guzik, Maciej, Savić, Sanja, Nikodinović-Runić, Jasmina, "Supplementary data for article: Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances, 13(34), 24112-24128. https://doi.org/10.1039/D3RA03021K" in RSC Advances (2023),
https://hdl.handle.net/21.15107/rcub_imagine_2060 .

TY  - JOUR
AU  - Solarz, Daria
AU  - Witko, Tomasz
AU  - Karcz, Robert
AU  - Malagurski, Ivana
AU  - Ponjavić, Marijana
AU  - Levic, Steva
AU  - Nešić, Aleksandra
AU  - Guzik, Maciej
AU  - Savić, Sanja
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://pubs.rsc.org/en/content/articlelanding/2023/ra/d3ra03021k
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2059
AB  - Polyhydroxyoctanoate, as a biocompatible and biodegradable biopolymer, represents an ideal candidate for biomedical applications. However, physical properties make it unsuitable for electrospinning, currently the most widely used technique for fabrication of fibrous scaffolds. To overcome this, it was blended with polylactic acid and polymer blend fibrous biomaterials were produced by electrospinning. The obtained PLA/PHO fibers were cylindrical, smaller in size, more hydrophilic and had a higher degree of biopolymer crystallinity and more favorable mechanical properties in comparison to the pure PLA sample. Cytotoxicity evaluation with human lung fibroblasts (MRC5 cells) combined with confocal microscopy were used to visualize mouse embryonic fibroblasts (MEF 3T3 cell line) migration and distribution showed that PLA/PHO samples support exceptional cell adhesion and viability, indicating excellent biocompatibility. The obtained results suggest that PLA/PHO fibrous biomaterials can be potentially used as biocompatible, biomimetic scaffolds for tissue engineering applications.
T2  - RSC Advances
T1  - Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications
EP  - 24128
IS  - 34
SP  - 24112
VL  - 13
DO  - 10.1039/D3RA03021K
ER  - 

@article{
author = "Solarz, Daria and Witko, Tomasz and Karcz, Robert and Malagurski, Ivana and Ponjavić, Marijana and Levic, Steva and Nešić, Aleksandra and Guzik, Maciej and Savić, Sanja and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "Polyhydroxyoctanoate, as a biocompatible and biodegradable biopolymer, represents an ideal candidate for biomedical applications. However, physical properties make it unsuitable for electrospinning, currently the most widely used technique for fabrication of fibrous scaffolds. To overcome this, it was blended with polylactic acid and polymer blend fibrous biomaterials were produced by electrospinning. The obtained PLA/PHO fibers were cylindrical, smaller in size, more hydrophilic and had a higher degree of biopolymer crystallinity and more favorable mechanical properties in comparison to the pure PLA sample. Cytotoxicity evaluation with human lung fibroblasts (MRC5 cells) combined with confocal microscopy were used to visualize mouse embryonic fibroblasts (MEF 3T3 cell line) migration and distribution showed that PLA/PHO samples support exceptional cell adhesion and viability, indicating excellent biocompatibility. The obtained results suggest that PLA/PHO fibrous biomaterials can be potentially used as biocompatible, biomimetic scaffolds for tissue engineering applications.",
journal = "RSC Advances",
title = "Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications",
pages = "24128-24112",
number = "34",
volume = "13",
doi = "10.1039/D3RA03021K"
}

Solarz, D., Witko, T., Karcz, R., Malagurski, I., Ponjavić, M., Levic, S., Nešić, A., Guzik, M., Savić, S.,& Nikodinović-Runić, J.. (2023). Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances, 13(34), 24112-24128.
https://doi.org/10.1039/D3RA03021K

Solarz D, Witko T, Karcz R, Malagurski I, Ponjavić M, Levic S, Nešić A, Guzik M, Savić S, Nikodinović-Runić J. Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications. in RSC Advances. 2023;13(34):24112-24128.
doi:10.1039/D3RA03021K .

Solarz, Daria, Witko, Tomasz, Karcz, Robert, Malagurski, Ivana, Ponjavić, Marijana, Levic, Steva, Nešić, Aleksandra, Guzik, Maciej, Savić, Sanja, Nikodinović-Runić, Jasmina, "Biological and physiochemical studies of electrospun polylactid/polyhydroxyoctanoate PLA/ P(3HO) scaffolds for tissue engineering applications" in RSC Advances, 13, no. 34 (2023):24112-24128,
https://doi.org/10.1039/D3RA03021K . .

TY  - CONF
AU  - Ponjavić, Marijana
AU  - Malagurski, Ivana
AU  - Salevic-Jelic, Ana
AU  - Lazić, Jelena
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2106
AB  - New film materials based on bacterial biomolecules polyhydroxyalkanoate (poly(3-
hydroxybutyrate-co-3-hydroxyvalerate) PHBV) and prodigiosin (PG) were produced by
solvent casting as a potential food packaging material. Film precursors were obtained in a
sustainable manner via microbial fermentation using waste stream-based substrates (cooking oil
and second-grade canned meat, after the expiry date). The incorporation of PG into the PHBV has
influenced the morphology and functionality of the obtained materials. PG acted as a nucleating
agent, affecting in turn PHBV/PG film surface morphology. The films were intensively colored,
transparent and blocked UV-light. An increase in PG content decreased film transparency but it
did not affect UV-blocking ability. Migration experiments have shown that films possess the
potential to release PG into lipophilic food simulant media where it has exhibited antioxidative
action. The obtained results suggest that PHBV/PG films can be potentially used as sustainable
and active food packaging materials.
PB  - Kragujevac : Institute for Information Technologies
C3  - 2nd International Conference on Chemo and Bioinformatics
T1  - UV-blocking sustainable food packaging based on polyhydroxyalkanoate and bacterial pigment prodigiosin
EP  - 1354
SP  - 1351
DO  - 10.46793/ICCBI23.351P
ER  - 

@conference{
author = "Ponjavić, Marijana and Malagurski, Ivana and Salevic-Jelic, Ana and Lazić, Jelena and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "New film materials based on bacterial biomolecules polyhydroxyalkanoate (poly(3-
hydroxybutyrate-co-3-hydroxyvalerate) PHBV) and prodigiosin (PG) were produced by
solvent casting as a potential food packaging material. Film precursors were obtained in a
sustainable manner via microbial fermentation using waste stream-based substrates (cooking oil
and second-grade canned meat, after the expiry date). The incorporation of PG into the PHBV has
influenced the morphology and functionality of the obtained materials. PG acted as a nucleating
agent, affecting in turn PHBV/PG film surface morphology. The films were intensively colored,
transparent and blocked UV-light. An increase in PG content decreased film transparency but it
did not affect UV-blocking ability. Migration experiments have shown that films possess the
potential to release PG into lipophilic food simulant media where it has exhibited antioxidative
action. The obtained results suggest that PHBV/PG films can be potentially used as sustainable
and active food packaging materials.",
publisher = "Kragujevac : Institute for Information Technologies",
journal = "2nd International Conference on Chemo and Bioinformatics",
title = "UV-blocking sustainable food packaging based on polyhydroxyalkanoate and bacterial pigment prodigiosin",
pages = "1354-1351",
doi = "10.46793/ICCBI23.351P"
}

Ponjavić, M., Malagurski, I., Salevic-Jelic, A., Lazić, J.,& Nikodinović-Runić, J.. (2023). UV-blocking sustainable food packaging based on polyhydroxyalkanoate and bacterial pigment prodigiosin. in 2nd International Conference on Chemo and Bioinformatics
Kragujevac : Institute for Information Technologies., 1351-1354.
https://doi.org/10.46793/ICCBI23.351P

Ponjavić M, Malagurski I, Salevic-Jelic A, Lazić J, Nikodinović-Runić J. UV-blocking sustainable food packaging based on polyhydroxyalkanoate and bacterial pigment prodigiosin. in 2nd International Conference on Chemo and Bioinformatics. 2023;:1351-1354.
doi:10.46793/ICCBI23.351P .

Ponjavić, Marijana, Malagurski, Ivana, Salevic-Jelic, Ana, Lazić, Jelena, Nikodinović-Runić, Jasmina, "UV-blocking sustainable food packaging based on polyhydroxyalkanoate and bacterial pigment prodigiosin" in 2nd International Conference on Chemo and Bioinformatics (2023):1351-1354,
https://doi.org/10.46793/ICCBI23.351P . .

TY  - CONF
AU  - Ponjavić, Marijana
AU  - Jeremić, Sanja
AU  - Malagurski, Ivana
AU  - Babu P., Ramesh
AU  - Rajasekaran, Divya
AU  - Topakas, Evangelos
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://afea.eventsair.com/10th-conference-of-mikrobiokosmos/abstract-book
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2236
AB  - The rapid increase in global plastics production is
also causing an accelerated environmental
pollution. Recently, biotechnological solutions and
enzymatic recycling of poly(ethylene terephthalate)
(PET) waste stream have been put forward and
commercialized1. Increasing recycling and
upcycling rates is the most effective model
approach to plastic circularity. However, mixed
plastic waste is still quite a challenge for both
recycling and upcycling technologies. This study is
focused on the eco-conversion of plastic waste
containing poly(ethylene terephthalate), PET, into
biopolymer, bacterial nanocellulose. Polymer mix
contained selection of commercial biodegradable
plastics (poly(lactic acid), PLA, poly(ε-caprolactone),
PCL, poly(hyoxyl butyrate), PHB) and PET. This
mixture was hydrolysed under aqueous conditions
and hydrolysate was used as carbon source for
Komagataeibacter medellinensis ID13488 and
bacterial nanocellulose (BNC) production. HPLC
analysis confirmed the presence of monomers and
dimers of polymer mix components indicating
existence of potential substrates for BNC
production. BNC production by K. medellinensis
was investigated and optimized in ter of the
amount of carbon source and growth conditions.
Under the most efficient rate in ter of yield, BNC
production was scaled up and the obtained
biopolymer was characterized. The structure of
produced BNC was confirmed by FTIR analysis,
thermal properties by DSC/TG analysis, and the
morphology of material by optical microscopy and
SEM analysis. This research demonstrates how to
put the mixed plastic waste stream into a circular
loop through the biotechnological conversion into
valuable biopolymer.
C3  - 10th Conference of Mikrobiokosmos
T1  - Conversion of mixed plastic waste containing PET into biopolymer bacterial nanocellulose
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2236
ER  - 

@conference{
author = "Ponjavić, Marijana and Jeremić, Sanja and Malagurski, Ivana and Babu P., Ramesh and Rajasekaran, Divya and Topakas, Evangelos and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "The rapid increase in global plastics production is
also causing an accelerated environmental
pollution. Recently, biotechnological solutions and
enzymatic recycling of poly(ethylene terephthalate)
(PET) waste stream have been put forward and
commercialized1. Increasing recycling and
upcycling rates is the most effective model
approach to plastic circularity. However, mixed
plastic waste is still quite a challenge for both
recycling and upcycling technologies. This study is
focused on the eco-conversion of plastic waste
containing poly(ethylene terephthalate), PET, into
biopolymer, bacterial nanocellulose. Polymer mix
contained selection of commercial biodegradable
plastics (poly(lactic acid), PLA, poly(ε-caprolactone),
PCL, poly(hyoxyl butyrate), PHB) and PET. This
mixture was hydrolysed under aqueous conditions
and hydrolysate was used as carbon source for
Komagataeibacter medellinensis ID13488 and
bacterial nanocellulose (BNC) production. HPLC
analysis confirmed the presence of monomers and
dimers of polymer mix components indicating
existence of potential substrates for BNC
production. BNC production by K. medellinensis
was investigated and optimized in ter of the
amount of carbon source and growth conditions.
Under the most efficient rate in ter of yield, BNC
production was scaled up and the obtained
biopolymer was characterized. The structure of
produced BNC was confirmed by FTIR analysis,
thermal properties by DSC/TG analysis, and the
morphology of material by optical microscopy and
SEM analysis. This research demonstrates how to
put the mixed plastic waste stream into a circular
loop through the biotechnological conversion into
valuable biopolymer.",
journal = "10th Conference of Mikrobiokosmos",
title = "Conversion of mixed plastic waste containing PET into biopolymer bacterial nanocellulose",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2236"
}

Ponjavić, M., Jeremić, S., Malagurski, I., Babu P., R., Rajasekaran, D., Topakas, E.,& Nikodinović-Runić, J.. (2023). Conversion of mixed plastic waste containing PET into biopolymer bacterial nanocellulose. in 10th Conference of Mikrobiokosmos.
https://hdl.handle.net/21.15107/rcub_imagine_2236

Ponjavić M, Jeremić S, Malagurski I, Babu P. R, Rajasekaran D, Topakas E, Nikodinović-Runić J. Conversion of mixed plastic waste containing PET into biopolymer bacterial nanocellulose. in 10th Conference of Mikrobiokosmos. 2023;.
https://hdl.handle.net/21.15107/rcub_imagine_2236 .

Ponjavić, Marijana, Jeremić, Sanja, Malagurski, Ivana, Babu P., Ramesh, Rajasekaran, Divya, Topakas, Evangelos, Nikodinović-Runić, Jasmina, "Conversion of mixed plastic waste containing PET into biopolymer bacterial nanocellulose" in 10th Conference of Mikrobiokosmos (2023),
https://hdl.handle.net/21.15107/rcub_imagine_2236 .

TY  - CONF
AU  - Ponjavić, Marijana
AU  - Babu P., Ramesh
AU  - Rajasekaran, Divya
AU  - Pantelić, Brana
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://www.accelevents.com/e/circular-bioeconomy-2023#about
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1924
AB  - Large amounts of polymers are discarded worldwide each year, leading to a significant
polymer waste in natural environment. The upcycling has been found as an efficient way to
transform polymer waste into high-value biomaterials meeting the conditions required for
circularity by being indefinitely recyclable, without reduction in value or usability.
The presented study refers to the upcycling of commercial biopolymers into bacterial
nanocellulose. Polymer blends, consisted of biodegradable polymers, such as poly(lactic acid),
PLA, poly(butylene succinate), PBS, and poly(ε-caprolactone), PCL. Polymers were hydrolyzed
and the obtained hydrolysates were investigated as potential carbon source for
K. medellinensis ID13488 growth and nanocellulose production. Degradation products were
analyzed using HPLC analysis. Different growth media, including tap water, HS medium,
absence / presence of glucose, were tested and bacterial nanocellulose growth was
confirmed under the most of the tested conditions. Once the BNC growth was set up, the BNC
production was scaled up and the obtained material was investigated in terms of structure
confirmation (FTIR analysis), thermal properties (DSC/TG analysis), morphology (optical
microscopy, AFM analysis) and crystallinity (XRD analysis). Finally, the full life cycle of mixed
biopolymers: from biodegradation to revalorization of end products into bacterial
nanocellulose appeared as perfect model approach to plastic circularity.
C3  - Biotechnology for a circular bioeconomy: carbon capture, waste recycling and mitigation of global warming
T1  - Revalorization of biodegradable polymers to valuable bacterial nanocellulose
SP  - 55
UR  - https://hdl.handle.net/21.15107/rcub_imagine_1924
ER  - 

@conference{
author = "Ponjavić, Marijana and Babu P., Ramesh and Rajasekaran, Divya and Pantelić, Brana and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "Large amounts of polymers are discarded worldwide each year, leading to a significant
polymer waste in natural environment. The upcycling has been found as an efficient way to
transform polymer waste into high-value biomaterials meeting the conditions required for
circularity by being indefinitely recyclable, without reduction in value or usability.
The presented study refers to the upcycling of commercial biopolymers into bacterial
nanocellulose. Polymer blends, consisted of biodegradable polymers, such as poly(lactic acid),
PLA, poly(butylene succinate), PBS, and poly(ε-caprolactone), PCL. Polymers were hydrolyzed
and the obtained hydrolysates were investigated as potential carbon source for
K. medellinensis ID13488 growth and nanocellulose production. Degradation products were
analyzed using HPLC analysis. Different growth media, including tap water, HS medium,
absence / presence of glucose, were tested and bacterial nanocellulose growth was
confirmed under the most of the tested conditions. Once the BNC growth was set up, the BNC
production was scaled up and the obtained material was investigated in terms of structure
confirmation (FTIR analysis), thermal properties (DSC/TG analysis), morphology (optical
microscopy, AFM analysis) and crystallinity (XRD analysis). Finally, the full life cycle of mixed
biopolymers: from biodegradation to revalorization of end products into bacterial
nanocellulose appeared as perfect model approach to plastic circularity.",
journal = "Biotechnology for a circular bioeconomy: carbon capture, waste recycling and mitigation of global warming",
title = "Revalorization of biodegradable polymers to valuable bacterial nanocellulose",
pages = "55",
url = "https://hdl.handle.net/21.15107/rcub_imagine_1924"
}

Ponjavić, M., Babu P., R., Rajasekaran, D., Pantelić, B.,& Nikodinović-Runić, J.. (2023). Revalorization of biodegradable polymers to valuable bacterial nanocellulose. in Biotechnology for a circular bioeconomy: carbon capture, waste recycling and mitigation of global warming, 55.
https://hdl.handle.net/21.15107/rcub_imagine_1924

Ponjavić M, Babu P. R, Rajasekaran D, Pantelić B, Nikodinović-Runić J. Revalorization of biodegradable polymers to valuable bacterial nanocellulose. in Biotechnology for a circular bioeconomy: carbon capture, waste recycling and mitigation of global warming. 2023;:55.
https://hdl.handle.net/21.15107/rcub_imagine_1924 .

Ponjavić, Marijana, Babu P., Ramesh, Rajasekaran, Divya, Pantelić, Brana, Nikodinović-Runić, Jasmina, "Revalorization of biodegradable polymers to valuable bacterial nanocellulose" in Biotechnology for a circular bioeconomy: carbon capture, waste recycling and mitigation of global warming (2023):55,
https://hdl.handle.net/21.15107/rcub_imagine_1924 .

TY  - CONF
AU  - Marija, Nenadović
AU  - Pantelić, Brana
AU  - Ponjavić, Marijana
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1916
AB  - Polyhydroxyalkanoates (PHA) are a green substitute for conventional plastics,
owing to their biological origin, biodegradability, biocompatibility and structural
diversity. However, environmental biodegradation of PHA is achieved in a time
frame of several months to several years, depending on environmental conditions,
and properties of both PHA and PHA degrading enzymes (PhaZ) [1]. Taking into
account the high production cost of PHA, landfilling at the end of life is not likely to
be cost-effective, so enzymatic biodegradation as an alternative offers an ecofriendly
bio-cyclable route to cost-effective PHA. Our study aims to tailor PhaZ
properties to create suitable biocatalysts for the industrially relevant time frame and
operating conditions. In order to do so, we decided to randomize PhaZ sequences
and functionally screen enzyme variants for accelerated PHA degradation and
improved biocatalyst stability. Up to this day, various phaZ genes have been mutated
solely for mechanistic purposes eg. Catalytic residue identification, and elucidation
of the substrate recognition process [2,3,4,5,6,7].
PB  - Beograd : Srpsko hemijsko društvo
C3  - 9. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, EnviroChem2023
T1  - Exploring PhaZ depolymerase sequence space for the bio-cyclable loop for biopolymers
EP  - 196
SP  - 195
VL  - 9
UR  - https://hdl.handle.net/21.15107/rcub_imagine_1916
ER  - 

@conference{
author = "Marija, Nenadović and Pantelić, Brana and Ponjavić, Marijana and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "Polyhydroxyalkanoates (PHA) are a green substitute for conventional plastics,
owing to their biological origin, biodegradability, biocompatibility and structural
diversity. However, environmental biodegradation of PHA is achieved in a time
frame of several months to several years, depending on environmental conditions,
and properties of both PHA and PHA degrading enzymes (PhaZ) [1]. Taking into
account the high production cost of PHA, landfilling at the end of life is not likely to
be cost-effective, so enzymatic biodegradation as an alternative offers an ecofriendly
bio-cyclable route to cost-effective PHA. Our study aims to tailor PhaZ
properties to create suitable biocatalysts for the industrially relevant time frame and
operating conditions. In order to do so, we decided to randomize PhaZ sequences
and functionally screen enzyme variants for accelerated PHA degradation and
improved biocatalyst stability. Up to this day, various phaZ genes have been mutated
solely for mechanistic purposes eg. Catalytic residue identification, and elucidation
of the substrate recognition process [2,3,4,5,6,7].",
publisher = "Beograd : Srpsko hemijsko društvo",
journal = "9. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, EnviroChem2023",
title = "Exploring PhaZ depolymerase sequence space for the bio-cyclable loop for biopolymers",
pages = "196-195",
volume = "9",
url = "https://hdl.handle.net/21.15107/rcub_imagine_1916"
}

Marija, N., Pantelić, B., Ponjavić, M.,& Nikodinović-Runić, J.. (2023). Exploring PhaZ depolymerase sequence space for the bio-cyclable loop for biopolymers. in 9. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, EnviroChem2023
Beograd : Srpsko hemijsko društvo., 9, 195-196.
https://hdl.handle.net/21.15107/rcub_imagine_1916

Marija N, Pantelić B, Ponjavić M, Nikodinović-Runić J. Exploring PhaZ depolymerase sequence space for the bio-cyclable loop for biopolymers. in 9. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, EnviroChem2023. 2023;9:195-196.
https://hdl.handle.net/21.15107/rcub_imagine_1916 .

Marija, Nenadović, Pantelić, Brana, Ponjavić, Marijana, Nikodinović-Runić, Jasmina, "Exploring PhaZ depolymerase sequence space for the bio-cyclable loop for biopolymers" in 9. simpozijum Hemija i zaštita životne sredine sa međunarodnim učešćem, EnviroChem2023, 9 (2023):195-196,
https://hdl.handle.net/21.15107/rcub_imagine_1916 .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Filipović, Vuk
AU  - Topakas, Evangelos
AU  - Karnaouri, Anthi
AU  - Živković, Jelena
AU  - Krgović, Nemanja
AU  - Mudrić, Jelena
AU  - Savikin, Katarina
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://www.mdpi.com/2304-8158/12/16/2995
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2025
AB  - Background: Bacterial nanocellulose (BNC) has gained in popularity over the years due to its outstanding properties such as renewability, biocompatibility, and bioavailability, and its use as an eco-friendly material of the future for replacing petrochemical products. (2) Methods: This research refers to the utilization of lignocellulose coming from wood waste via enzymatic hydrolysis to produce biopolymer BNC with an accumulation rate of 0.09 mg/mL/day. Besides its significant contribution to the sustainability, circularity, and valorization of biomass products, the obtained BNC was functionalized through the adsorption of black raspberry extract (BR) by simple soaking. (3) Results: BR contained 77.25 ± 0.23 mg GAE/g of total phenolics and 27.42 ± 0.32 mg CGE/g of total anthocyanins. The antioxidant and antimicrobial activity of BR was evaluated by DPPH (60.51 ± 0.18 µg/mL) and FRAP (1.66 ± 0.03 mmol Fe2+/g) and using a standard disc diffusion assay, respectively. The successful synthesis and interactions between BNC and BR were confirmed by FTIR analysis, while the morphology of the new nutrient-enriched material was investigated by SEM analysis. Moreover, the in vitro release kinetics of a main active compound (cyanidin-3-O-rutinoside) was tested in different release media. (4) Conclusions: The upcycling process of lignocellulose into enriched BNC has been demonstrated. All findings emphasize the potential of BNC–BR as a sustainable food industry material.
T2  - Foods
T2  - Foods
T1  - Two-Step Upcycling Process of Lignocellulose into Edible Bacterial Nanocellulose with Black Raspberry Extract as an Active Ingredient
IS  - 16
SP  - 2995
VL  - 12
DO  - 10.3390/foods12162995
ER  - 

@article{
author = "Ponjavić, Marijana and Filipović, Vuk and Topakas, Evangelos and Karnaouri, Anthi and Živković, Jelena and Krgović, Nemanja and Mudrić, Jelena and Savikin, Katarina and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "Background: Bacterial nanocellulose (BNC) has gained in popularity over the years due to its outstanding properties such as renewability, biocompatibility, and bioavailability, and its use as an eco-friendly material of the future for replacing petrochemical products. (2) Methods: This research refers to the utilization of lignocellulose coming from wood waste via enzymatic hydrolysis to produce biopolymer BNC with an accumulation rate of 0.09 mg/mL/day. Besides its significant contribution to the sustainability, circularity, and valorization of biomass products, the obtained BNC was functionalized through the adsorption of black raspberry extract (BR) by simple soaking. (3) Results: BR contained 77.25 ± 0.23 mg GAE/g of total phenolics and 27.42 ± 0.32 mg CGE/g of total anthocyanins. The antioxidant and antimicrobial activity of BR was evaluated by DPPH (60.51 ± 0.18 µg/mL) and FRAP (1.66 ± 0.03 mmol Fe2+/g) and using a standard disc diffusion assay, respectively. The successful synthesis and interactions between BNC and BR were confirmed by FTIR analysis, while the morphology of the new nutrient-enriched material was investigated by SEM analysis. Moreover, the in vitro release kinetics of a main active compound (cyanidin-3-O-rutinoside) was tested in different release media. (4) Conclusions: The upcycling process of lignocellulose into enriched BNC has been demonstrated. All findings emphasize the potential of BNC–BR as a sustainable food industry material.",
journal = "Foods, Foods",
title = "Two-Step Upcycling Process of Lignocellulose into Edible Bacterial Nanocellulose with Black Raspberry Extract as an Active Ingredient",
number = "16",
pages = "2995",
volume = "12",
doi = "10.3390/foods12162995"
}

Ponjavić, M., Filipović, V., Topakas, E., Karnaouri, A., Živković, J., Krgović, N., Mudrić, J., Savikin, K.,& Nikodinović-Runić, J.. (2023). Two-Step Upcycling Process of Lignocellulose into Edible Bacterial Nanocellulose with Black Raspberry Extract as an Active Ingredient. in Foods, 12(16), 2995.
https://doi.org/10.3390/foods12162995

Ponjavić M, Filipović V, Topakas E, Karnaouri A, Živković J, Krgović N, Mudrić J, Savikin K, Nikodinović-Runić J. Two-Step Upcycling Process of Lignocellulose into Edible Bacterial Nanocellulose with Black Raspberry Extract as an Active Ingredient. in Foods. 2023;12(16):2995.
doi:10.3390/foods12162995 .

Ponjavić, Marijana, Filipović, Vuk, Topakas, Evangelos, Karnaouri, Anthi, Živković, Jelena, Krgović, Nemanja, Mudrić, Jelena, Savikin, Katarina, Nikodinović-Runić, Jasmina, "Two-Step Upcycling Process of Lignocellulose into Edible Bacterial Nanocellulose with Black Raspberry Extract as an Active Ingredient" in Foods, 12, no. 16 (2023):2995,
https://doi.org/10.3390/foods12162995 . .

TY  - JOUR
AU  - Kovačević, Aleksandar
AU  - Radoičić, Marija
AU  - Marković, Darka
AU  - Ponjavić, Marijana
AU  - Nikodinović-Runić, Jasmina
AU  - Radetić, Maja
PY  - 2023
UR  - https://www.sciencedirect.com/science/article/pii/S2352186423001669
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1840
AB  - Loose assemblies of cellulose fibers could be employed in the clean-up of oil spills, but the difficulty to separate them from the spill after use makes them impractical. In an effort to tackle this issue, a non-woven sorbent based on recycled jute fibers from the carpet industry was developed. To enhance the porosity and hydrophobicity/oleophilicity of the sorbent, carbonization in an inert atmosphere was carried out. A comparison in oil sorption performance between non-carbonized and carbonized sorbents was made by evaluating the oil capacity in a water medium, buoyancy, oil retention and reusability. Carbonization of sorbent resulted in more than doubled oil sorption capacity independent of oil viscosity. Oil viscosity did not affect the oil sorption capacity of non-carbonized sorbent. Carbonized sorbent showed superior buoyancy in water even after 24 hours, oil retention of approximately 60–80% after 3 hours and only 12–20% decline of oil sorption capacity after five repeated sorption/desorption trials. However, the ability of oiled non-carbonized sorbent to efficiently biodegrade in model compost (up to 45% weight loss after 10 weeks) makes it a sustainable candidate for oil spill clean-up.
T2  - Environmental Technology & Innovation
T2  - Environmental Technology & InnovationEnvironmental Technology & Innovation
T1  - Non-woven sorbent based on recycled jute fibers for efficient oil spill clean-up: From production to biodegradation
SP  - 103170
VL  - 31
DO  - 10.1016/j.eti.2023.103170
ER  - 

@article{
author = "Kovačević, Aleksandar and Radoičić, Marija and Marković, Darka and Ponjavić, Marijana and Nikodinović-Runić, Jasmina and Radetić, Maja",
year = "2023",
abstract = "Loose assemblies of cellulose fibers could be employed in the clean-up of oil spills, but the difficulty to separate them from the spill after use makes them impractical. In an effort to tackle this issue, a non-woven sorbent based on recycled jute fibers from the carpet industry was developed. To enhance the porosity and hydrophobicity/oleophilicity of the sorbent, carbonization in an inert atmosphere was carried out. A comparison in oil sorption performance between non-carbonized and carbonized sorbents was made by evaluating the oil capacity in a water medium, buoyancy, oil retention and reusability. Carbonization of sorbent resulted in more than doubled oil sorption capacity independent of oil viscosity. Oil viscosity did not affect the oil sorption capacity of non-carbonized sorbent. Carbonized sorbent showed superior buoyancy in water even after 24 hours, oil retention of approximately 60–80% after 3 hours and only 12–20% decline of oil sorption capacity after five repeated sorption/desorption trials. However, the ability of oiled non-carbonized sorbent to efficiently biodegrade in model compost (up to 45% weight loss after 10 weeks) makes it a sustainable candidate for oil spill clean-up.",
journal = "Environmental Technology & Innovation, Environmental Technology & InnovationEnvironmental Technology & Innovation",
title = "Non-woven sorbent based on recycled jute fibers for efficient oil spill clean-up: From production to biodegradation",
pages = "103170",
volume = "31",
doi = "10.1016/j.eti.2023.103170"
}

Kovačević, A., Radoičić, M., Marković, D., Ponjavić, M., Nikodinović-Runić, J.,& Radetić, M.. (2023). Non-woven sorbent based on recycled jute fibers for efficient oil spill clean-up: From production to biodegradation. in Environmental Technology & Innovation, 31, 103170.
https://doi.org/10.1016/j.eti.2023.103170

Kovačević A, Radoičić M, Marković D, Ponjavić M, Nikodinović-Runić J, Radetić M. Non-woven sorbent based on recycled jute fibers for efficient oil spill clean-up: From production to biodegradation. in Environmental Technology & Innovation. 2023;31:103170.
doi:10.1016/j.eti.2023.103170 .

Kovačević, Aleksandar, Radoičić, Marija, Marković, Darka, Ponjavić, Marijana, Nikodinović-Runić, Jasmina, Radetić, Maja, "Non-woven sorbent based on recycled jute fibers for efficient oil spill clean-up: From production to biodegradation" in Environmental Technology & Innovation, 31 (2023):103170,
https://doi.org/10.1016/j.eti.2023.103170 . .

TY  - CONF
AU  - Sourkouni, G.
AU  - Kalogirou, Ch.
AU  - Papadimitriou, N.
AU  - Nenadović, Marija
AU  - Ponjavić, Marijana
AU  - Argirusis, N.
AU  - Pandis, P.
AU  - Rajasekaran, D.
AU  - Padamati, R.
AU  - Ferraro, A.
AU  - Nikodinović-Runić, Jasmina
AU  - Argirusis, Chr.
PY  - 2023
UR  - http://chania2023.uest.gr/poster.html
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2024
AB  - Plastics are artificial synthetic organic polymers that have been used in every area of daily life. However, because of their slow degradation rate, their use
is contentious. The treatment of the surface of the sample is considered necessary as enzymatic or bacterial attach is not possible, if the plastic surface
environment is not ideal. The main topic of this work is the investigation of the effect of atmospheric dielectric barrier discharge (DBD) plasma on the near
surface structure of polylactic acid (PLA) samples, which, in turn, can promote the adhesion of enzymes or bacteria for further biodegradation. In general,
plasma processes can already be considered as inherently environmental technologies.
Plasma processes enable resource saving through high energy utilization efficiency and thus, are environ-mentally friendly technologies. Atmospheric
pressure discharges (APDs) are useful because of their specific advantages over low-pressure ones. They do not need expensive vacuum equipment, and
generate nonthermal plasmas, which are more suitable for assembly line processes. Hence, this category of discharges has significant industrial
applications. The use of a dielectric barrier in the discharge gap helps prevent spark formation. DBDs exhibit two major discharge modes: filamentary and
glow (homogeneous). The glow discharge mode has obvious advantages over the filamentary one for applications such as treatment of surfaces and
deposition of thin films. Glow mode discharges with average power densities comparable to those of filamentary discharges are of enormous interest for
applications in which reliable control is required.
Here we will present the increased adhesion of bacteria strains on DBD plasma treated PLA foils which can lead to a better degradation of the PLA. X-ray
photoelectron spectroscopy (XPS) measurements of the foils prior to and after the treatment proved the changes on the polymer surface. A short
discussion of the possibilities the treatment opens is given.
C3  - 10th International Conference on Sustainable Solid Waste Management Chania
T1  - Plasma assisted bio-degradation  of poly-lactic acid (PLA)
VL  - 10
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2024
ER  - 

@conference{
author = "Sourkouni, G. and Kalogirou, Ch. and Papadimitriou, N. and Nenadović, Marija and Ponjavić, Marijana and Argirusis, N. and Pandis, P. and Rajasekaran, D. and Padamati, R. and Ferraro, A. and Nikodinović-Runić, Jasmina and Argirusis, Chr.",
year = "2023",
abstract = "Plastics are artificial synthetic organic polymers that have been used in every area of daily life. However, because of their slow degradation rate, their use
is contentious. The treatment of the surface of the sample is considered necessary as enzymatic or bacterial attach is not possible, if the plastic surface
environment is not ideal. The main topic of this work is the investigation of the effect of atmospheric dielectric barrier discharge (DBD) plasma on the near
surface structure of polylactic acid (PLA) samples, which, in turn, can promote the adhesion of enzymes or bacteria for further biodegradation. In general,
plasma processes can already be considered as inherently environmental technologies.
Plasma processes enable resource saving through high energy utilization efficiency and thus, are environ-mentally friendly technologies. Atmospheric
pressure discharges (APDs) are useful because of their specific advantages over low-pressure ones. They do not need expensive vacuum equipment, and
generate nonthermal plasmas, which are more suitable for assembly line processes. Hence, this category of discharges has significant industrial
applications. The use of a dielectric barrier in the discharge gap helps prevent spark formation. DBDs exhibit two major discharge modes: filamentary and
glow (homogeneous). The glow discharge mode has obvious advantages over the filamentary one for applications such as treatment of surfaces and
deposition of thin films. Glow mode discharges with average power densities comparable to those of filamentary discharges are of enormous interest for
applications in which reliable control is required.
Here we will present the increased adhesion of bacteria strains on DBD plasma treated PLA foils which can lead to a better degradation of the PLA. X-ray
photoelectron spectroscopy (XPS) measurements of the foils prior to and after the treatment proved the changes on the polymer surface. A short
discussion of the possibilities the treatment opens is given.",
journal = "10th International Conference on Sustainable Solid Waste Management Chania",
title = "Plasma assisted bio-degradation  of poly-lactic acid (PLA)",
volume = "10",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2024"
}

Sourkouni, G., Kalogirou, Ch., Papadimitriou, N., Nenadović, M., Ponjavić, M., Argirusis, N., Pandis, P., Rajasekaran, D., Padamati, R., Ferraro, A., Nikodinović-Runić, J.,& Argirusis, Chr.. (2023). Plasma assisted bio-degradation  of poly-lactic acid (PLA). in 10th International Conference on Sustainable Solid Waste Management Chania, 10.
https://hdl.handle.net/21.15107/rcub_imagine_2024

Sourkouni G, Kalogirou C, Papadimitriou N, Nenadović M, Ponjavić M, Argirusis N, Pandis P, Rajasekaran D, Padamati R, Ferraro A, Nikodinović-Runić J, Argirusis C. Plasma assisted bio-degradation  of poly-lactic acid (PLA). in 10th International Conference on Sustainable Solid Waste Management Chania. 2023;10.
https://hdl.handle.net/21.15107/rcub_imagine_2024 .

Sourkouni, G., Kalogirou, Ch., Papadimitriou, N., Nenadović, Marija, Ponjavić, Marijana, Argirusis, N., Pandis, P., Rajasekaran, D., Padamati, R., Ferraro, A., Nikodinović-Runić, Jasmina, Argirusis, Chr., "Plasma assisted bio-degradation  of poly-lactic acid (PLA)" in 10th International Conference on Sustainable Solid Waste Management Chania, 10 (2023),
https://hdl.handle.net/21.15107/rcub_imagine_2024 .

TY  - CONF
AU  - Pešović, Tijana
AU  - Kovačević, Aleksandar
AU  - Nikodinović-Runić, Jasmina
AU  - Ponjavić, Marijana
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/2207
AB  - In the fight against oil and it's derivatives pollution, adsorbents play a crucial role in
efficient removal of these harmful substances from the environment. Jute, a natural plant
fiber, is gaining increasing attention as a potential adsorbent for oil due to high porosity,
good physical and chemical characteristics, biodegradability, and sustainability [1]. The
aim of this study was to investigate the biodegradable properties of jute used as an
absorbent for oil in a liquid medium and model compost. Materials and methods: The
study monitored weight loss in oil-contaminated jute (NWSO) and compared it with
control jute (NWS). Morphological changes in jute fibers were observed with optical
microscopy and SEM analysis. Gas chromatography (GC-MS) was used for the
detection of hydrocarbons in degraded jute. Enzymatic activity changes in compost soil
were tracked. Bacterial strain isolation was done to assess growth on pure and oilcontaminated
jute, with subsequent taxonomic identification. Results: NWSO samples
were degraded more efficiently compared to clean jute with a weight reduction of 20%
in NWSO compared to 5% in NWS. Microscopic and SEM analyses confirmed
morphological changes in jute fibers after degradation. A decrease in hydrocarbon
concentration after degradation was shown. Enzymatic activity tests provided additional
insights into the composting process. The study also identified diverse bacterial strains
capable of oil degradation, primarily belonging to Bacillus and Microbacterium genera.
Conclusion: The study demonstrates the superior biodegradation of NWSO compared
to NWS. The promising role of jute in sustainable bioremediation strategies leading to
reduced harm from oil pollution has been demonstrated.
PB  - Belgrade : Serbian Chemical Society and Serbian Young Chemists’ Club
C3  - 9th Conference of Young Chemists of Serbia
T1  - Biological degradation of recycled jute used as an adsorbent for crude oil
EP  - 95
SP  - 95
UR  - https://hdl.handle.net/21.15107/rcub_imagine_2207
ER  - 

@conference{
author = "Pešović, Tijana and Kovačević, Aleksandar and Nikodinović-Runić, Jasmina and Ponjavić, Marijana",
year = "2023",
abstract = "In the fight against oil and it's derivatives pollution, adsorbents play a crucial role in
efficient removal of these harmful substances from the environment. Jute, a natural plant
fiber, is gaining increasing attention as a potential adsorbent for oil due to high porosity,
good physical and chemical characteristics, biodegradability, and sustainability [1]. The
aim of this study was to investigate the biodegradable properties of jute used as an
absorbent for oil in a liquid medium and model compost. Materials and methods: The
study monitored weight loss in oil-contaminated jute (NWSO) and compared it with
control jute (NWS). Morphological changes in jute fibers were observed with optical
microscopy and SEM analysis. Gas chromatography (GC-MS) was used for the
detection of hydrocarbons in degraded jute. Enzymatic activity changes in compost soil
were tracked. Bacterial strain isolation was done to assess growth on pure and oilcontaminated
jute, with subsequent taxonomic identification. Results: NWSO samples
were degraded more efficiently compared to clean jute with a weight reduction of 20%
in NWSO compared to 5% in NWS. Microscopic and SEM analyses confirmed
morphological changes in jute fibers after degradation. A decrease in hydrocarbon
concentration after degradation was shown. Enzymatic activity tests provided additional
insights into the composting process. The study also identified diverse bacterial strains
capable of oil degradation, primarily belonging to Bacillus and Microbacterium genera.
Conclusion: The study demonstrates the superior biodegradation of NWSO compared
to NWS. The promising role of jute in sustainable bioremediation strategies leading to
reduced harm from oil pollution has been demonstrated.",
publisher = "Belgrade : Serbian Chemical Society and Serbian Young Chemists’ Club",
journal = "9th Conference of Young Chemists of Serbia",
title = "Biological degradation of recycled jute used as an adsorbent for crude oil",
pages = "95-95",
url = "https://hdl.handle.net/21.15107/rcub_imagine_2207"
}

Pešović, T., Kovačević, A., Nikodinović-Runić, J.,& Ponjavić, M.. (2023). Biological degradation of recycled jute used as an adsorbent for crude oil. in 9th Conference of Young Chemists of Serbia
Belgrade : Serbian Chemical Society and Serbian Young Chemists’ Club., 95-95.
https://hdl.handle.net/21.15107/rcub_imagine_2207

Pešović T, Kovačević A, Nikodinović-Runić J, Ponjavić M. Biological degradation of recycled jute used as an adsorbent for crude oil. in 9th Conference of Young Chemists of Serbia. 2023;:95-95.
https://hdl.handle.net/21.15107/rcub_imagine_2207 .

Pešović, Tijana, Kovačević, Aleksandar, Nikodinović-Runić, Jasmina, Ponjavić, Marijana, "Biological degradation of recycled jute used as an adsorbent for crude oil" in 9th Conference of Young Chemists of Serbia (2023):95-95,
https://hdl.handle.net/21.15107/rcub_imagine_2207 .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Malagurski, Ivana
AU  - Lazić, Jelena
AU  - Jeremić, Sanja
AU  - Pavlović, Vladimir
AU  - Prlainović, Nevena
AU  - Maksimović, Vesna
AU  - Cosović, Vladan
AU  - Atanase, Leonard Ionut
AU  - Freitas, Filomena
AU  - Matos, Mariana
AU  - Nikodinović-Runić, Jasmina
PY  - 2023
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1714
AB  - The quest for sustainable biomaterials with excellent biocompatibility and tailorable properties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high production costs and the lack of bioactivity limit their market penetration. To address this, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was combined with a bacterial pigment with strong anticancer activity, prodigiosin (PG), to obtain functionally enhanced PHBV-based biomaterials. The samples were produced in the form of films 115.6–118.8 µm in thickness using the solvent casting method. The effects of PG incorporation on the physical properties (morphology, biopolymer crystallinity and thermal stability) and functionality of the obtained biomaterials were investigated. PG has acted as a nucleating agent, in turn affecting the degree of crystallinity, thermal stability and morphology of the films. All samples with PG had a more organized internal structure and higher melting and degradation temperatures. The calculated degree of crystallinity of the PHBV copolymer was 53%, while the PG1, PG3 and PG3 films had values of 64.0%, 63.9% and 69.2%, respectively. Cytotoxicity studies have shown the excellent anticancer activity of films against HCT116 (colon cancer) cells, thus advancing PHBV biomedical application potential.
T2  - International Journal of Molecular Sciences
T2  - International Journal of Molecular Sciences
T1  - Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin
IS  - 3
SP  - 1906
VL  - 24
DO  - 10.3390/ijms24031906
ER  - 

@article{
author = "Ponjavić, Marijana and Malagurski, Ivana and Lazić, Jelena and Jeremić, Sanja and Pavlović, Vladimir and Prlainović, Nevena and Maksimović, Vesna and Cosović, Vladan and Atanase, Leonard Ionut and Freitas, Filomena and Matos, Mariana and Nikodinović-Runić, Jasmina",
year = "2023",
abstract = "The quest for sustainable biomaterials with excellent biocompatibility and tailorable properties has put polyhydroxyalkanoates (PHAs) into the research spotlight. However, high production costs and the lack of bioactivity limit their market penetration. To address this, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) was combined with a bacterial pigment with strong anticancer activity, prodigiosin (PG), to obtain functionally enhanced PHBV-based biomaterials. The samples were produced in the form of films 115.6–118.8 µm in thickness using the solvent casting method. The effects of PG incorporation on the physical properties (morphology, biopolymer crystallinity and thermal stability) and functionality of the obtained biomaterials were investigated. PG has acted as a nucleating agent, in turn affecting the degree of crystallinity, thermal stability and morphology of the films. All samples with PG had a more organized internal structure and higher melting and degradation temperatures. The calculated degree of crystallinity of the PHBV copolymer was 53%, while the PG1, PG3 and PG3 films had values of 64.0%, 63.9% and 69.2%, respectively. Cytotoxicity studies have shown the excellent anticancer activity of films against HCT116 (colon cancer) cells, thus advancing PHBV biomedical application potential.",
journal = "International Journal of Molecular Sciences, International Journal of Molecular Sciences",
title = "Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin",
number = "3",
pages = "1906",
volume = "24",
doi = "10.3390/ijms24031906"
}

Ponjavić, M., Malagurski, I., Lazić, J., Jeremić, S., Pavlović, V., Prlainović, N., Maksimović, V., Cosović, V., Atanase, L. I., Freitas, F., Matos, M.,& Nikodinović-Runić, J.. (2023). Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin. in International Journal of Molecular Sciences, 24(3), 1906.
https://doi.org/10.3390/ijms24031906

Ponjavić M, Malagurski I, Lazić J, Jeremić S, Pavlović V, Prlainović N, Maksimović V, Cosović V, Atanase LI, Freitas F, Matos M, Nikodinović-Runić J. Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin. in International Journal of Molecular Sciences. 2023;24(3):1906.
doi:10.3390/ijms24031906 .

Ponjavić, Marijana, Malagurski, Ivana, Lazić, Jelena, Jeremić, Sanja, Pavlović, Vladimir, Prlainović, Nevena, Maksimović, Vesna, Cosović, Vladan, Atanase, Leonard Ionut, Freitas, Filomena, Matos, Mariana, Nikodinović-Runić, Jasmina, "Advancing PHBV Biomedical Potential with the Incorporation of Bacterial Biopigment Prodigiosin" in International Journal of Molecular Sciences, 24, no. 3 (2023):1906,
https://doi.org/10.3390/ijms24031906 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Stevanovic, Sanja
AU  - Nikodinović-Runić, Jasmina
AU  - Jeremić, Sanja
AU  - Cosovic, Vladan R.
AU  - Maksimovic, Vesna
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1659
AB  - Bacterial nanocellulose, BNC, has emerged as a new class of nanomaterials recognized as renewable, biodegradable, biocompatible and material for versatile applications. BNC also proved as a perfect support matrix for metallic nanoparticle synthesis and appeared as suitable alternative for widely used carbon based materials. Following the idea to replace commonly used carbon based materials for platinum supports with the green and sustainable one, BNC appeared as an excellent candidate. Herein, microwave assisted synthesis has been reported for the first time for platinum nanoparticles supported on BNC as green material. Bacterial nanocelullose-platinum catalyst, Pt/BNC, was investigated by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), atomic force microscopy (AFM), X-ray diffractometry (XRD) and transmission-electron microscopy (TEM) analysis. The obtained results confirmed successful synthesis of new Pt-based catalyst. It was found that Pt/BNC catalyst has high electrocatalytic performance in methanol oxidation reaction. Green/sustainable catalytic system is highly desirable and provided by the elegant microwave assisted synthesis of Pt/BNC will pave the way for a larger scale application and expedite the market penetration of such fuel cells.
T2  - International Journal of Biological Macromolecules
T2  - International Journal of Biological MacromoleculesInternational Journal of Biological Macromolecules
T1  - Bacterial nanocellulose as green support of platinum nanoparticles for effective methanol oxidation
EP  - 1484
SP  - 1474
VL  - 223
DO  - 10.1016/j.ijbiomac.2022.10.278
ER  - 

@article{
author = "Ponjavić, Marijana and Stevanovic, Sanja and Nikodinović-Runić, Jasmina and Jeremić, Sanja and Cosovic, Vladan R. and Maksimovic, Vesna",
year = "2022",
abstract = "Bacterial nanocellulose, BNC, has emerged as a new class of nanomaterials recognized as renewable, biodegradable, biocompatible and material for versatile applications. BNC also proved as a perfect support matrix for metallic nanoparticle synthesis and appeared as suitable alternative for widely used carbon based materials. Following the idea to replace commonly used carbon based materials for platinum supports with the green and sustainable one, BNC appeared as an excellent candidate. Herein, microwave assisted synthesis has been reported for the first time for platinum nanoparticles supported on BNC as green material. Bacterial nanocelullose-platinum catalyst, Pt/BNC, was investigated by Fourier transform infrared spectroscopy (FTIR), differential scanning calorimetry (DSC), atomic force microscopy (AFM), X-ray diffractometry (XRD) and transmission-electron microscopy (TEM) analysis. The obtained results confirmed successful synthesis of new Pt-based catalyst. It was found that Pt/BNC catalyst has high electrocatalytic performance in methanol oxidation reaction. Green/sustainable catalytic system is highly desirable and provided by the elegant microwave assisted synthesis of Pt/BNC will pave the way for a larger scale application and expedite the market penetration of such fuel cells.",
journal = "International Journal of Biological Macromolecules, International Journal of Biological MacromoleculesInternational Journal of Biological Macromolecules",
title = "Bacterial nanocellulose as green support of platinum nanoparticles for effective methanol oxidation",
pages = "1484-1474",
volume = "223",
doi = "10.1016/j.ijbiomac.2022.10.278"
}

Ponjavić, M., Stevanovic, S., Nikodinović-Runić, J., Jeremić, S., Cosovic, V. R.,& Maksimovic, V.. (2022). Bacterial nanocellulose as green support of platinum nanoparticles for effective methanol oxidation. in International Journal of Biological Macromolecules, 223, 1474-1484.
https://doi.org/10.1016/j.ijbiomac.2022.10.278

Ponjavić M, Stevanovic S, Nikodinović-Runić J, Jeremić S, Cosovic VR, Maksimovic V. Bacterial nanocellulose as green support of platinum nanoparticles for effective methanol oxidation. in International Journal of Biological Macromolecules. 2022;223:1474-1484.
doi:10.1016/j.ijbiomac.2022.10.278 .

Ponjavić, Marijana, Stevanovic, Sanja, Nikodinović-Runić, Jasmina, Jeremić, Sanja, Cosovic, Vladan R., Maksimovic, Vesna, "Bacterial nanocellulose as green support of platinum nanoparticles for effective methanol oxidation" in International Journal of Biological Macromolecules, 223 (2022):1474-1484,
https://doi.org/10.1016/j.ijbiomac.2022.10.278 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Jevtić, Sanja
AU  - Jeremić, Sanja
AU  - Đokić, Lidija
AU  - Donlagić, Jasna
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1580
AB  - The present study reports the potential application of star-shaped poly(epsilon-caprolactones) with different number of arms as new drug delivery matrix. Linear and star-shaped PCL ibuprofen loaded microspheres were prepared using oil-in-water (o/w) solvent evaporation technique and characterized with FTIR, DSC, XRD and SEM analysis. High yield, encapsulation efficiency and drug loadings were obtained for all microspheres. FTIR analysis revealed the existence of interactions between polymer matrix and drug, while the DSC analysis suggested that drug was encapsulated in an amorphous form. SEM analysis confirmed that regular, spherical in shape star-shaped microspheres, with diameter between 80 and 90 mu n, were obtained, while quite larger microspheres, 110 mu m, were prepared from linear PCL. The advantage of using starshaped PCL microspheres instead of linear PCL was seen from drug release profiles which demonstrated higher amount of drug released from star-shaped polymer matrix as a consequence of their branched, flexible structure. Microspheres prepared from the polymers with the most branched structure showed the highest amount of the released drug after 24 h. Finally, cytotoxicity tests, performed using normal human fibroblasts (MRCS), indicated the absence of cytotoxicity at lower concentrations of microspheres proving the great potential of star-shaped PCL systems in comparison to linear ones.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Star-shaped poly(epsilon-caprolactones) with well-defined architecture as potential drug carriers
DO  - 10.2298/JSC220202032P
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Jevtić, Sanja and Jeremić, Sanja and Đokić, Lidija and Donlagić, Jasna",
year = "2022",
abstract = "The present study reports the potential application of star-shaped poly(epsilon-caprolactones) with different number of arms as new drug delivery matrix. Linear and star-shaped PCL ibuprofen loaded microspheres were prepared using oil-in-water (o/w) solvent evaporation technique and characterized with FTIR, DSC, XRD and SEM analysis. High yield, encapsulation efficiency and drug loadings were obtained for all microspheres. FTIR analysis revealed the existence of interactions between polymer matrix and drug, while the DSC analysis suggested that drug was encapsulated in an amorphous form. SEM analysis confirmed that regular, spherical in shape star-shaped microspheres, with diameter between 80 and 90 mu n, were obtained, while quite larger microspheres, 110 mu m, were prepared from linear PCL. The advantage of using starshaped PCL microspheres instead of linear PCL was seen from drug release profiles which demonstrated higher amount of drug released from star-shaped polymer matrix as a consequence of their branched, flexible structure. Microspheres prepared from the polymers with the most branched structure showed the highest amount of the released drug after 24 h. Finally, cytotoxicity tests, performed using normal human fibroblasts (MRCS), indicated the absence of cytotoxicity at lower concentrations of microspheres proving the great potential of star-shaped PCL systems in comparison to linear ones.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Star-shaped poly(epsilon-caprolactones) with well-defined architecture as potential drug carriers",
doi = "10.2298/JSC220202032P"
}

Ponjavić, M., Nikolić, M. S., Jevtić, S., Jeremić, S., Đokić, L.,& Donlagić, J.. (2022). Star-shaped poly(epsilon-caprolactones) with well-defined architecture as potential drug carriers. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd..
https://doi.org/10.2298/JSC220202032P

Ponjavić M, Nikolić MS, Jevtić S, Jeremić S, Đokić L, Donlagić J. Star-shaped poly(epsilon-caprolactones) with well-defined architecture as potential drug carriers. in Journal of the Serbian Chemical Society. 2022;.
doi:10.2298/JSC220202032P .

Ponjavić, Marijana, Nikolić, Marija S., Jevtić, Sanja, Jeremić, Sanja, Đokić, Lidija, Donlagić, Jasna, "Star-shaped poly(epsilon-caprolactones) with well-defined architecture as potential drug carriers" in Journal of the Serbian Chemical Society (2022),
https://doi.org/10.2298/JSC220202032P . .

TY  - JOUR
AU  - Atanase, Leonard Ionut
AU  - Salhi, Slim
AU  - Cucoveica, Oana
AU  - Ponjavić, Marijana
AU  - Nikodinović-Runić, Jasmina
AU  - Delaite, Christelle
PY  - 2022
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1520
AB  - Biodegradable polymers contain chains that are hydrolytically or enzymatically cleaved, resulting in soluble degradation products. Biodegradability is particularly desired in biomedical applications, in which degradation of the polymer ensures clearance from the body and eliminates the need for retrieval or explant. In this study, a homologues series of poly(epsilon-caprolactone)-b-poly(ethylene adipate)-b-poly(epsilon-caprolactone) (PCL-b-PEA-b-PCL) block copolymers, with constant PEA molar mass and different PCL sequence lengths was obtained. The starting point of these copolymers was a dihydroxy-PEA precursor with a molar mass (M-n) of 2500 g/mol. Mn values of the PCL varied between 1000 and 10,000 g/mol. Both the precursors and the copolymers were characterized using different physicochemical methods, such as: NMR, SEC, Maldi-TOFF, DSC, and ATG. The molecular characteristics of the copolymers were in a direct correlation with the sequence length of the PCL. Enzymatic degradability studies were also conducted by using cell-free extract containing Pseudomonas aeruginosa PAO1 for 10 and 21 days, and it appeared that the presence of the PEA central sequence has an important influence on the biodegradability of the copolymer samples. In fact, copolymer PCL7000-PEA(2500)-PCL7000 had a weight loss of around 50% after 10 days whereas the weight loss of the homopolymer PCL, with a similar M-n of 14,000 g/mol, was only 6%. The results obtained in this study indicate that these copolymer samples can be further used for the preparation of drug delivery systems with modulated biodegradability.
PB  - MDPI, Basel
T2  - Polymers
T1  - Biodegradability Assessment of Polyester Copolymers Based on Poly(ethylene adipate) and Poly(epsilon-caprolactone)
IS  - 18
VL  - 14
DO  - 10.3390/polym14183736
ER  - 

@article{
author = "Atanase, Leonard Ionut and Salhi, Slim and Cucoveica, Oana and Ponjavić, Marijana and Nikodinović-Runić, Jasmina and Delaite, Christelle",
year = "2022",
abstract = "Biodegradable polymers contain chains that are hydrolytically or enzymatically cleaved, resulting in soluble degradation products. Biodegradability is particularly desired in biomedical applications, in which degradation of the polymer ensures clearance from the body and eliminates the need for retrieval or explant. In this study, a homologues series of poly(epsilon-caprolactone)-b-poly(ethylene adipate)-b-poly(epsilon-caprolactone) (PCL-b-PEA-b-PCL) block copolymers, with constant PEA molar mass and different PCL sequence lengths was obtained. The starting point of these copolymers was a dihydroxy-PEA precursor with a molar mass (M-n) of 2500 g/mol. Mn values of the PCL varied between 1000 and 10,000 g/mol. Both the precursors and the copolymers were characterized using different physicochemical methods, such as: NMR, SEC, Maldi-TOFF, DSC, and ATG. The molecular characteristics of the copolymers were in a direct correlation with the sequence length of the PCL. Enzymatic degradability studies were also conducted by using cell-free extract containing Pseudomonas aeruginosa PAO1 for 10 and 21 days, and it appeared that the presence of the PEA central sequence has an important influence on the biodegradability of the copolymer samples. In fact, copolymer PCL7000-PEA(2500)-PCL7000 had a weight loss of around 50% after 10 days whereas the weight loss of the homopolymer PCL, with a similar M-n of 14,000 g/mol, was only 6%. The results obtained in this study indicate that these copolymer samples can be further used for the preparation of drug delivery systems with modulated biodegradability.",
publisher = "MDPI, Basel",
journal = "Polymers",
title = "Biodegradability Assessment of Polyester Copolymers Based on Poly(ethylene adipate) and Poly(epsilon-caprolactone)",
number = "18",
volume = "14",
doi = "10.3390/polym14183736"
}

Atanase, L. I., Salhi, S., Cucoveica, O., Ponjavić, M., Nikodinović-Runić, J.,& Delaite, C.. (2022). Biodegradability Assessment of Polyester Copolymers Based on Poly(ethylene adipate) and Poly(epsilon-caprolactone). in Polymers
MDPI, Basel., 14(18).
https://doi.org/10.3390/polym14183736

Atanase LI, Salhi S, Cucoveica O, Ponjavić M, Nikodinović-Runić J, Delaite C. Biodegradability Assessment of Polyester Copolymers Based on Poly(ethylene adipate) and Poly(epsilon-caprolactone). in Polymers. 2022;14(18).
doi:10.3390/polym14183736 .

Atanase, Leonard Ionut, Salhi, Slim, Cucoveica, Oana, Ponjavić, Marijana, Nikodinović-Runić, Jasmina, Delaite, Christelle, "Biodegradability Assessment of Polyester Copolymers Based on Poly(ethylene adipate) and Poly(epsilon-caprolactone)" in Polymers, 14, no. 18 (2022),
https://doi.org/10.3390/polym14183736 . .

TY  - JOUR
AU  - Pantelić, Brana
AU  - Ponjavić, Marijana
AU  - Janković, Vukašin
AU  - Aleksić, Ivana
AU  - Stevanović, Sanja
AU  - Murray, James
AU  - Fournet, Margaret Brennan
AU  - Nikodinović-Runić, Jasmina
PY  - 2021
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1470
AB  - Meeting the challenge of circularity for plastics requires amenability to repurposing post-use, as equivalent or upcycled products. In a compelling advancement, complete circularity for a biodegradable polyvinyl alcohol/thermoplastic starch (PVA/TPS) food packaging film was demonstrated by bioconversion to high-market-value biopigments and polyhydroxybutyrate (PHB) polyesters. The PVA/TPS film mechanical properties (tensile strength (sigma(u)), 22.2 & PLUSMN; 4.3 MPa; strain at break (epsilon(u)), 325 & PLUSMN; 73%; and Young's modulus (E), 53-250 MPa) compared closely with low-density polyethylene (LDPE) grades used for food packaging. Strong solubility of the PVA/TPS film in water was a pertinent feature, facilitating suitability as a carbon source for bioprocessing and microbial degradation. Biodegradability of the film with greater than 50% weight loss occurred within 30 days of incubation at 37 & DEG;C in a model compost. Up to 22% of the PVA/TPS film substrate conversion to biomass was achieved using three bacterial strains, Ralstonia eutropha H16 (Cupriavidus necator ATCC 17699), Streptomyces sp. JS520, and Bacillus subtilis ATCC6633. For the first time, production of the valuable biopigment (undecylprodigiosin) by Streptomyces sp. JS520 of 5.3 mg/mL and the production of PHB biopolymer at 7.8% of cell dry weight by Ralstonia eutropha H16 from this substrate were reported. This low-energy, low-carbon post-use PVA/TPS film upcycling model approach to plastic circularity demonstrates marked progress in the quest for sustainable and circular plastic solutions.
PB  - MDPI, Basel
T2  - Polymers
T1  - Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer
IS  - 21
VL  - 13
DO  - 10.3390/polym13213692
ER  - 

@article{
author = "Pantelić, Brana and Ponjavić, Marijana and Janković, Vukašin and Aleksić, Ivana and Stevanović, Sanja and Murray, James and Fournet, Margaret Brennan and Nikodinović-Runić, Jasmina",
year = "2021",
abstract = "Meeting the challenge of circularity for plastics requires amenability to repurposing post-use, as equivalent or upcycled products. In a compelling advancement, complete circularity for a biodegradable polyvinyl alcohol/thermoplastic starch (PVA/TPS) food packaging film was demonstrated by bioconversion to high-market-value biopigments and polyhydroxybutyrate (PHB) polyesters. The PVA/TPS film mechanical properties (tensile strength (sigma(u)), 22.2 & PLUSMN; 4.3 MPa; strain at break (epsilon(u)), 325 & PLUSMN; 73%; and Young's modulus (E), 53-250 MPa) compared closely with low-density polyethylene (LDPE) grades used for food packaging. Strong solubility of the PVA/TPS film in water was a pertinent feature, facilitating suitability as a carbon source for bioprocessing and microbial degradation. Biodegradability of the film with greater than 50% weight loss occurred within 30 days of incubation at 37 & DEG;C in a model compost. Up to 22% of the PVA/TPS film substrate conversion to biomass was achieved using three bacterial strains, Ralstonia eutropha H16 (Cupriavidus necator ATCC 17699), Streptomyces sp. JS520, and Bacillus subtilis ATCC6633. For the first time, production of the valuable biopigment (undecylprodigiosin) by Streptomyces sp. JS520 of 5.3 mg/mL and the production of PHB biopolymer at 7.8% of cell dry weight by Ralstonia eutropha H16 from this substrate were reported. This low-energy, low-carbon post-use PVA/TPS film upcycling model approach to plastic circularity demonstrates marked progress in the quest for sustainable and circular plastic solutions.",
publisher = "MDPI, Basel",
journal = "Polymers",
title = "Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer",
number = "21",
volume = "13",
doi = "10.3390/polym13213692"
}

Pantelić, B., Ponjavić, M., Janković, V., Aleksić, I., Stevanović, S., Murray, J., Fournet, M. B.,& Nikodinović-Runić, J.. (2021). Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer. in Polymers
MDPI, Basel., 13(21).
https://doi.org/10.3390/polym13213692

Pantelić B, Ponjavić M, Janković V, Aleksić I, Stevanović S, Murray J, Fournet MB, Nikodinović-Runić J. Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer. in Polymers. 2021;13(21).
doi:10.3390/polym13213692 .

Pantelić, Brana, Ponjavić, Marijana, Janković, Vukašin, Aleksić, Ivana, Stevanović, Sanja, Murray, James, Fournet, Margaret Brennan, Nikodinović-Runić, Jasmina, "Upcycling Biodegradable PVA/Starch Film to a Bacterial Biopigment and Biopolymer" in Polymers, 13, no. 21 (2021),
https://doi.org/10.3390/polym13213692 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Stevanović, Sanja
AU  - Nikodinović-Runić, Jasmina
AU  - Jeremić, Sanja
AU  - Pavić, Aleksandar
AU  - Đonlagić, Jasna
PY  - 2020
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1354
AB  - Star-shaped polymers of biodegradable aliphatic polyester, poly(epsilon-caprolactone), PCL, with different number of arms (three, four, and six) were synthesized by ring-opening polymerization initiated by multifunctional alcohols used as cores. As potential biomaterials, synthesized star-shaped poly(epsilon-caprolactone)s,sPCL, were thoroughly characterized in terms of their degradation under different pH conditions and in respect to their cytotoxicity. The in vitro degradation was performed in phosphate buffer (pH 7.4) and hydrochloric acid solution (pH 1.0) over 5 weeks. Degradation ofsPCL films was followed by the weight loss measurements, GPC, FTIR, and AFM analysis. While the most of the samples were stable against the abiotic hydrolysis at pH 7.4 after 5 weeks of degradation, degradation was significantly accelerated in the acidic medium. Degradation rate of polymer films was affected by the polymer architecture and molecular weight. The molecular weight profiles during the degradation revealed random chain scission of the ester bonds indicating bulk degradation mechanism of hydrolysis at pH 7.4, while acidic hydrolysis proceeded through the bulk degradation associated with surface erosion, confirmed by AFM. The in vitro toxicity tests, cytotoxicity applying normal human fibroblasts (MRC5) and embryotoxicity assessment (using zebra fish model,Danio rerio), suggested those polymeric materials as suitable for biomedical application.
PB  - Sage Publications Ltd, London
T2  - Journal of Bioactive and Compatible Polymers
T1  - Hydrolytic degradation of star-shaped poly(epsilon-caprolactone)s with different number of arms and their cytotoxic effects
EP  - 537
IS  - 6
SP  - 517
VL  - 35
DO  - 10.1177/0883911520951826
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Stevanović, Sanja and Nikodinović-Runić, Jasmina and Jeremić, Sanja and Pavić, Aleksandar and Đonlagić, Jasna",
year = "2020",
abstract = "Star-shaped polymers of biodegradable aliphatic polyester, poly(epsilon-caprolactone), PCL, with different number of arms (three, four, and six) were synthesized by ring-opening polymerization initiated by multifunctional alcohols used as cores. As potential biomaterials, synthesized star-shaped poly(epsilon-caprolactone)s,sPCL, were thoroughly characterized in terms of their degradation under different pH conditions and in respect to their cytotoxicity. The in vitro degradation was performed in phosphate buffer (pH 7.4) and hydrochloric acid solution (pH 1.0) over 5 weeks. Degradation ofsPCL films was followed by the weight loss measurements, GPC, FTIR, and AFM analysis. While the most of the samples were stable against the abiotic hydrolysis at pH 7.4 after 5 weeks of degradation, degradation was significantly accelerated in the acidic medium. Degradation rate of polymer films was affected by the polymer architecture and molecular weight. The molecular weight profiles during the degradation revealed random chain scission of the ester bonds indicating bulk degradation mechanism of hydrolysis at pH 7.4, while acidic hydrolysis proceeded through the bulk degradation associated with surface erosion, confirmed by AFM. The in vitro toxicity tests, cytotoxicity applying normal human fibroblasts (MRC5) and embryotoxicity assessment (using zebra fish model,Danio rerio), suggested those polymeric materials as suitable for biomedical application.",
publisher = "Sage Publications Ltd, London",
journal = "Journal of Bioactive and Compatible Polymers",
title = "Hydrolytic degradation of star-shaped poly(epsilon-caprolactone)s with different number of arms and their cytotoxic effects",
pages = "537-517",
number = "6",
volume = "35",
doi = "10.1177/0883911520951826"
}

Ponjavić, M., Nikolić, M. S., Stevanović, S., Nikodinović-Runić, J., Jeremić, S., Pavić, A.,& Đonlagić, J.. (2020). Hydrolytic degradation of star-shaped poly(epsilon-caprolactone)s with different number of arms and their cytotoxic effects. in Journal of Bioactive and Compatible Polymers
Sage Publications Ltd, London., 35(6), 517-537.
https://doi.org/10.1177/0883911520951826

Ponjavić M, Nikolić MS, Stevanović S, Nikodinović-Runić J, Jeremić S, Pavić A, Đonlagić J. Hydrolytic degradation of star-shaped poly(epsilon-caprolactone)s with different number of arms and their cytotoxic effects. in Journal of Bioactive and Compatible Polymers. 2020;35(6):517-537.
doi:10.1177/0883911520951826 .

Ponjavić, Marijana, Nikolić, Marija S., Stevanović, Sanja, Nikodinović-Runić, Jasmina, Jeremić, Sanja, Pavić, Aleksandar, Đonlagić, Jasna, "Hydrolytic degradation of star-shaped poly(epsilon-caprolactone)s with different number of arms and their cytotoxic effects" in Journal of Bioactive and Compatible Polymers, 35, no. 6 (2020):517-537,
https://doi.org/10.1177/0883911520951826 . .

TY  - JOUR
AU  - Mandić, Mina
AU  - Spasić, Jelena
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Cosović, Vladan R.
AU  - O'Connor, Kevin
AU  - Nikodinović-Runić, Jasmina
AU  - Đokić, Lidija
AU  - Jeremić, Sanja
PY  - 2019
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1760
AB  - Petrochemical plastics are generally recalcitrant to microbial degradation and accumulate in the environment. Biodegradable polymers obtained synthetically like poly(epsilon-caprolactone) (PCL) or poly-hydroxyalkanoates (PHA), obtained biotechnologically, have shown great potential as a replacement for petroleum-based plastics. Nevertheless, their biodegradation and environmental faith have been less examined. In this study, thin films of PCL (200 mu m) and medium chain length PHA (mcl-PHA, 70 M fraction of 3-hydroxyoctanoate and 30 M fraction of 3-hydroxydecanoate, 600 mu m) were exposed to total protein preparations (extracellular proteins combined with a crude cell extract) of soil isolates Pseudomonas chiororaphis B-561 and Streptomyces sp. BV315 that had been grown on waste cooking oil as a sole carbon source. Biodegradation potential of two polyesters was evaluated in buffer with total protein preparations and in a laboratory compost model system augmented with selected bacteria. Overall, PCL showed better biodegradation properties in comparison to mcl-PHA. Both materials showed surface erosion after 4-weeks of exposure to total protein preparations of both strains, with a moderate weight loss of 1.3% when P. chlororaphis13-561 was utilized. In laboratory compost model system PCL and mcl-PHA showed significant weight loss ranging from 13 to 17% when Streptomyces sp. BV315 culture was used. Similar weight loss of PCL and mcl-PHA was achieved for 4 and 8 weeks, respectively indicating slower degradation of mcl-PHA. Growth on waste cooking oil as a sole carbon source increased the potential of both tested strains to degrade PCL and mcl-PHA, making them good candidates for augmentation of compost cultures in waste management of both waste cooking oils and biodegradable polymers.
PB  - Elsevier Sci Ltd, Oxford
T2  - Polymer Degradation and Stability
T1  - Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil
EP  - 168
SP  - 160
VL  - 162
DO  - 10.1016/j.polymdegradstab.2019.02.012
ER  - 

@article{
author = "Mandić, Mina and Spasić, Jelena and Ponjavić, Marijana and Nikolić, Marija S. and Cosović, Vladan R. and O'Connor, Kevin and Nikodinović-Runić, Jasmina and Đokić, Lidija and Jeremić, Sanja",
year = "2019",
abstract = "Petrochemical plastics are generally recalcitrant to microbial degradation and accumulate in the environment. Biodegradable polymers obtained synthetically like poly(epsilon-caprolactone) (PCL) or poly-hydroxyalkanoates (PHA), obtained biotechnologically, have shown great potential as a replacement for petroleum-based plastics. Nevertheless, their biodegradation and environmental faith have been less examined. In this study, thin films of PCL (200 mu m) and medium chain length PHA (mcl-PHA, 70 M fraction of 3-hydroxyoctanoate and 30 M fraction of 3-hydroxydecanoate, 600 mu m) were exposed to total protein preparations (extracellular proteins combined with a crude cell extract) of soil isolates Pseudomonas chiororaphis B-561 and Streptomyces sp. BV315 that had been grown on waste cooking oil as a sole carbon source. Biodegradation potential of two polyesters was evaluated in buffer with total protein preparations and in a laboratory compost model system augmented with selected bacteria. Overall, PCL showed better biodegradation properties in comparison to mcl-PHA. Both materials showed surface erosion after 4-weeks of exposure to total protein preparations of both strains, with a moderate weight loss of 1.3% when P. chlororaphis13-561 was utilized. In laboratory compost model system PCL and mcl-PHA showed significant weight loss ranging from 13 to 17% when Streptomyces sp. BV315 culture was used. Similar weight loss of PCL and mcl-PHA was achieved for 4 and 8 weeks, respectively indicating slower degradation of mcl-PHA. Growth on waste cooking oil as a sole carbon source increased the potential of both tested strains to degrade PCL and mcl-PHA, making them good candidates for augmentation of compost cultures in waste management of both waste cooking oils and biodegradable polymers.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Polymer Degradation and Stability",
title = "Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil",
pages = "168-160",
volume = "162",
doi = "10.1016/j.polymdegradstab.2019.02.012"
}

Mandić, M., Spasić, J., Ponjavić, M., Nikolić, M. S., Cosović, V. R., O'Connor, K., Nikodinović-Runić, J., Đokić, L.,& Jeremić, S.. (2019). Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil. in Polymer Degradation and Stability
Elsevier Sci Ltd, Oxford., 162, 160-168.
https://doi.org/10.1016/j.polymdegradstab.2019.02.012

Mandić M, Spasić J, Ponjavić M, Nikolić MS, Cosović VR, O'Connor K, Nikodinović-Runić J, Đokić L, Jeremić S. Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil. in Polymer Degradation and Stability. 2019;162:160-168.
doi:10.1016/j.polymdegradstab.2019.02.012 .

Mandić, Mina, Spasić, Jelena, Ponjavić, Marijana, Nikolić, Marija S., Cosović, Vladan R., O'Connor, Kevin, Nikodinović-Runić, Jasmina, Đokić, Lidija, Jeremić, Sanja, "Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil" in Polymer Degradation and Stability, 162 (2019):160-168,
https://doi.org/10.1016/j.polymdegradstab.2019.02.012 . .

TY  - JOUR
AU  - Mandić, Mina
AU  - Spasić, Jelena
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Cosović, Vladan R.
AU  - O'Connor, Kevin
AU  - Nikodinović-Runić, Jasmina
AU  - Đokić, Lidija
AU  - Jeremić, Sanja
PY  - 2019
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1246
AB  - Petrochemical plastics are generally recalcitrant to microbial degradation and accumulate in the environment. Biodegradable polymers obtained synthetically like poly(epsilon-caprolactone) (PCL) or poly-hydroxyalkanoates (PHA), obtained biotechnologically, have shown great potential as a replacement for petroleum-based plastics. Nevertheless, their biodegradation and environmental faith have been less examined. In this study, thin films of PCL (200 mu m) and medium chain length PHA (mcl-PHA, 70 M fraction of 3-hydroxyoctanoate and 30 M fraction of 3-hydroxydecanoate, 600 mu m) were exposed to total protein preparations (extracellular proteins combined with a crude cell extract) of soil isolates Pseudomonas chiororaphis B-561 and Streptomyces sp. BV315 that had been grown on waste cooking oil as a sole carbon source. Biodegradation potential of two polyesters was evaluated in buffer with total protein preparations and in a laboratory compost model system augmented with selected bacteria. Overall, PCL showed better biodegradation properties in comparison to mcl-PHA. Both materials showed surface erosion after 4-weeks of exposure to total protein preparations of both strains, with a moderate weight loss of 1.3% when P. chlororaphis13-561 was utilized. In laboratory compost model system PCL and mcl-PHA showed significant weight loss ranging from 13 to 17% when Streptomyces sp. BV315 culture was used. Similar weight loss of PCL and mcl-PHA was achieved for 4 and 8 weeks, respectively indicating slower degradation of mcl-PHA. Growth on waste cooking oil as a sole carbon source increased the potential of both tested strains to degrade PCL and mcl-PHA, making them good candidates for augmentation of compost cultures in waste management of both waste cooking oils and biodegradable polymers.
PB  - Elsevier Sci Ltd, Oxford
T2  - Polymer Degradation and Stability
T1  - Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil
EP  - 168
SP  - 160
VL  - 162
DO  - 10.1016/j.polymdegradstab.2019.02.012
ER  - 

@article{
author = "Mandić, Mina and Spasić, Jelena and Ponjavić, Marijana and Nikolić, Marija S. and Cosović, Vladan R. and O'Connor, Kevin and Nikodinović-Runić, Jasmina and Đokić, Lidija and Jeremić, Sanja",
year = "2019",
abstract = "Petrochemical plastics are generally recalcitrant to microbial degradation and accumulate in the environment. Biodegradable polymers obtained synthetically like poly(epsilon-caprolactone) (PCL) or poly-hydroxyalkanoates (PHA), obtained biotechnologically, have shown great potential as a replacement for petroleum-based plastics. Nevertheless, their biodegradation and environmental faith have been less examined. In this study, thin films of PCL (200 mu m) and medium chain length PHA (mcl-PHA, 70 M fraction of 3-hydroxyoctanoate and 30 M fraction of 3-hydroxydecanoate, 600 mu m) were exposed to total protein preparations (extracellular proteins combined with a crude cell extract) of soil isolates Pseudomonas chiororaphis B-561 and Streptomyces sp. BV315 that had been grown on waste cooking oil as a sole carbon source. Biodegradation potential of two polyesters was evaluated in buffer with total protein preparations and in a laboratory compost model system augmented with selected bacteria. Overall, PCL showed better biodegradation properties in comparison to mcl-PHA. Both materials showed surface erosion after 4-weeks of exposure to total protein preparations of both strains, with a moderate weight loss of 1.3% when P. chlororaphis13-561 was utilized. In laboratory compost model system PCL and mcl-PHA showed significant weight loss ranging from 13 to 17% when Streptomyces sp. BV315 culture was used. Similar weight loss of PCL and mcl-PHA was achieved for 4 and 8 weeks, respectively indicating slower degradation of mcl-PHA. Growth on waste cooking oil as a sole carbon source increased the potential of both tested strains to degrade PCL and mcl-PHA, making them good candidates for augmentation of compost cultures in waste management of both waste cooking oils and biodegradable polymers.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Polymer Degradation and Stability",
title = "Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil",
pages = "168-160",
volume = "162",
doi = "10.1016/j.polymdegradstab.2019.02.012"
}

Mandić, M., Spasić, J., Ponjavić, M., Nikolić, M. S., Cosović, V. R., O'Connor, K., Nikodinović-Runić, J., Đokić, L.,& Jeremić, S.. (2019). Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil. in Polymer Degradation and Stability
Elsevier Sci Ltd, Oxford., 162, 160-168.
https://doi.org/10.1016/j.polymdegradstab.2019.02.012

Mandić M, Spasić J, Ponjavić M, Nikolić MS, Cosović VR, O'Connor K, Nikodinović-Runić J, Đokić L, Jeremić S. Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil. in Polymer Degradation and Stability. 2019;162:160-168.
doi:10.1016/j.polymdegradstab.2019.02.012 .

Mandić, Mina, Spasić, Jelena, Ponjavić, Marijana, Nikolić, Marija S., Cosović, Vladan R., O'Connor, Kevin, Nikodinović-Runić, Jasmina, Đokić, Lidija, Jeremić, Sanja, "Biodegradation of poly(epsilon-caprolactone) (PCL) and medium chain length polyhydroxyalkanoate (mcl-PHA) using whole cells and cell free protein preparations of Pseudomonas and Streptomyces strains grown on waste cooking oil" in Polymer Degradation and Stability, 162 (2019):160-168,
https://doi.org/10.1016/j.polymdegradstab.2019.02.012 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Nikodinović-Runić, Jasmina
AU  - Ilić-Tomić, Tatjana
AU  - Đonlagić, J.
PY  - 2019
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1294
AB  - In order to create a new drug delivery system, the ibuprofen-loaded triblock copolymer PCL/PEO/PCL (PCEC) microspheres with a low PEO content ( lt 2 wt%) were prepared by oil in water (o/w) solvent evaporation technique. The influence of PEO content, molecular weight of a polymer matrix and drug loading on the ibuprofen release profiles were evaluated. The interactions between polymer matrix and ibuprofen were detected by FTIR analysis. The presence of hydrophilic PEO segment in PCL chains caused the decrease in particle size, which further had a great impact on the drug release kinetics, i.e., initially faster release and significantly higher quantity of released drug compared to neat PCL. Ibuprofen release behavior from polymer matrix was governed by a diffusion process. In vitro cytotoxicity tests revealed that empty PCL and PCEC microspheres were not toxic at low concentrations, while ibuprofen-loaded microspheres exhibited cytotoxicity correlated with amounts of incorporated drug.
PB  - Taylor & Francis As, Oslo
T2  - International Journal of Polymeric Materials and Polymeric Biomaterials
T1  - Controlled drug release carriers based on PCL/PEO/PCL block copolymers
EP  - 318
IS  - 6
SP  - 308
VL  - 68
DO  - 10.1080/00914037.2018.1445631
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Nikodinović-Runić, Jasmina and Ilić-Tomić, Tatjana and Đonlagić, J.",
year = "2019",
abstract = "In order to create a new drug delivery system, the ibuprofen-loaded triblock copolymer PCL/PEO/PCL (PCEC) microspheres with a low PEO content ( lt 2 wt%) were prepared by oil in water (o/w) solvent evaporation technique. The influence of PEO content, molecular weight of a polymer matrix and drug loading on the ibuprofen release profiles were evaluated. The interactions between polymer matrix and ibuprofen were detected by FTIR analysis. The presence of hydrophilic PEO segment in PCL chains caused the decrease in particle size, which further had a great impact on the drug release kinetics, i.e., initially faster release and significantly higher quantity of released drug compared to neat PCL. Ibuprofen release behavior from polymer matrix was governed by a diffusion process. In vitro cytotoxicity tests revealed that empty PCL and PCEC microspheres were not toxic at low concentrations, while ibuprofen-loaded microspheres exhibited cytotoxicity correlated with amounts of incorporated drug.",
publisher = "Taylor & Francis As, Oslo",
journal = "International Journal of Polymeric Materials and Polymeric Biomaterials",
title = "Controlled drug release carriers based on PCL/PEO/PCL block copolymers",
pages = "318-308",
number = "6",
volume = "68",
doi = "10.1080/00914037.2018.1445631"
}

Ponjavić, M., Nikolić, M. S., Nikodinović-Runić, J., Ilić-Tomić, T.,& Đonlagić, J.. (2019). Controlled drug release carriers based on PCL/PEO/PCL block copolymers. in International Journal of Polymeric Materials and Polymeric Biomaterials
Taylor & Francis As, Oslo., 68(6), 308-318.
https://doi.org/10.1080/00914037.2018.1445631

Ponjavić M, Nikolić MS, Nikodinović-Runić J, Ilić-Tomić T, Đonlagić J. Controlled drug release carriers based on PCL/PEO/PCL block copolymers. in International Journal of Polymeric Materials and Polymeric Biomaterials. 2019;68(6):308-318.
doi:10.1080/00914037.2018.1445631 .

Ponjavić, Marijana, Nikolić, Marija S., Nikodinović-Runić, Jasmina, Ilić-Tomić, Tatjana, Đonlagić, J., "Controlled drug release carriers based on PCL/PEO/PCL block copolymers" in International Journal of Polymeric Materials and Polymeric Biomaterials, 68, no. 6 (2019):308-318,
https://doi.org/10.1080/00914037.2018.1445631 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Jeremić, Sanja
AU  - Đokić, Lidija
AU  - Nikodinović-Runić, Jasmina
AU  - Cosović, Vladan R.
AU  - Đonlagić, Jasna
PY  - 2018
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1125
AB  - Hydrolytic, enzymatic degradation and composting under controlled conditions of series of triblock PCL/PEO copolymers, PCEC, with central short PEO block (M (n) 400 g/mol) are presented and compared with homopolymer (PCL). The PCEC copolymers, synthesized via ring-opening polymerization of epsilon-caprolactone, were characterized by H-1 NMR, quantitative C-13 NMR, GPC, DSC and WAXS. The introduction of the PEO central segment ( lt  2 wt%) in PCL chains significantly affected thermal degradation and crystallization behavior, while the hydrophobicity was slightly reduced as confirmed by water absorption and moisture uptake experiments. Hydrolytic degradation studies in phosphate buffer after 8 weeks indicated a small weight loss, while FTIR analysis detected changes in crystallinity indexes and GPC measurements revealed bulk degradation. Enzymatic degradation tested by cell-free extracts containing Pseudomonas aeruginosa PAO1 confirmed high enzyme activity throughout the surface causing morphological changes detected by optical microscopy and AFM analysis. The changes in roughness of polymer films revealed surface erosion mechanism of enzymatic degradation. Copolymer with the highest content of PEO segment and the lowest molecular weight showed better degradation ability compared to PCL and other copolymers. Furthermore, composting of polymer films in a model compost system at 37 A degrees C resulted in significant degradation of the all synthesized block copolymers.
PB  - Springer/Plenum Publishers, New York
T2  - Journal of Polymers and the Environment
T1  - Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers
EP  - 2359
IS  - 6
SP  - 2346
VL  - 26
DO  - 10.1007/s10924-017-1130-2
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Jeremić, Sanja and Đokić, Lidija and Nikodinović-Runić, Jasmina and Cosović, Vladan R. and Đonlagić, Jasna",
year = "2018",
abstract = "Hydrolytic, enzymatic degradation and composting under controlled conditions of series of triblock PCL/PEO copolymers, PCEC, with central short PEO block (M (n) 400 g/mol) are presented and compared with homopolymer (PCL). The PCEC copolymers, synthesized via ring-opening polymerization of epsilon-caprolactone, were characterized by H-1 NMR, quantitative C-13 NMR, GPC, DSC and WAXS. The introduction of the PEO central segment ( lt  2 wt%) in PCL chains significantly affected thermal degradation and crystallization behavior, while the hydrophobicity was slightly reduced as confirmed by water absorption and moisture uptake experiments. Hydrolytic degradation studies in phosphate buffer after 8 weeks indicated a small weight loss, while FTIR analysis detected changes in crystallinity indexes and GPC measurements revealed bulk degradation. Enzymatic degradation tested by cell-free extracts containing Pseudomonas aeruginosa PAO1 confirmed high enzyme activity throughout the surface causing morphological changes detected by optical microscopy and AFM analysis. The changes in roughness of polymer films revealed surface erosion mechanism of enzymatic degradation. Copolymer with the highest content of PEO segment and the lowest molecular weight showed better degradation ability compared to PCL and other copolymers. Furthermore, composting of polymer films in a model compost system at 37 A degrees C resulted in significant degradation of the all synthesized block copolymers.",
publisher = "Springer/Plenum Publishers, New York",
journal = "Journal of Polymers and the Environment",
title = "Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers",
pages = "2359-2346",
number = "6",
volume = "26",
doi = "10.1007/s10924-017-1130-2"
}

Ponjavić, M., Nikolić, M. S., Jeremić, S., Đokić, L., Nikodinović-Runić, J., Cosović, V. R.,& Đonlagić, J.. (2018). Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers. in Journal of Polymers and the Environment
Springer/Plenum Publishers, New York., 26(6), 2346-2359.
https://doi.org/10.1007/s10924-017-1130-2

Ponjavić M, Nikolić MS, Jeremić S, Đokić L, Nikodinović-Runić J, Cosović VR, Đonlagić J. Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers. in Journal of Polymers and the Environment. 2018;26(6):2346-2359.
doi:10.1007/s10924-017-1130-2 .

Ponjavić, Marijana, Nikolić, Marija S., Jeremić, Sanja, Đokić, Lidija, Nikodinović-Runić, Jasmina, Cosović, Vladan R., Đonlagić, Jasna, "Influence of Short Central PEO Segment on Hydrolytic and Enzymatic Degradation of Triblock PCL Copolymers" in Journal of Polymers and the Environment, 26, no. 6 (2018):2346-2359,
https://doi.org/10.1007/s10924-017-1130-2 . .

TY  - JOUR
AU  - Ponjavić, Marijana
AU  - Nikolić, Marija S.
AU  - Nikodinović-Runić, Jasmina
AU  - Jeremić, Sanja
AU  - Stevanović, Sanja
AU  - Đonlagić, Jasna
PY  - 2017
UR  - https://imagine.imgge.bg.ac.rs/handle/123456789/1064
AB  - Short-term hydrolytic and enzymatic degradation of poly(epsilon-caprolactone) (PCL), one series of triblock (PCL/PEO/PCL) and the other of diblock (PCL/PEO) copolymers, with a low content of hydrophilic PEO segments is presented. The effect of the introduction of PEO as the central or lateral segment in the PCL chain on copolymer hydrolysis and biodegradation properties was investigated. FUR results revealed higher hydrolytic degradation susceptibility of diblock copolymers due to a higher hydrophilicity compared to PCL and triblock copolymers. Enzymatic degradation was tested using cell-free extracts of Pseudomonas aeruginosa PAO1, for two weeks by following the weight loss, changes in surface roughness, and changes in carbonyl and crystallinity index. The results confirmed that all samples underwent enzymatic degradation through surface erosion which was accompanied with a decrease in molecular weights. Diblock copolymers showed significantly higher weight loss and decrease in molecular weight in comparison to PCL itself and triblock copolymers. AFM analysis confirmed significant surface erosion and increase in RMS values. In addition, biodegradation of polymer films was tested in compost model system at 37 degrees C, where an effective degradation of block copolymers was observed.
PB  - Elsevier Sci Ltd, Oxford
T2  - Polymer Testing
T1  - Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions
EP  - 77
SP  - 67
VL  - 57
DO  - 10.1016/j.polymertesting.2016.11.018
ER  - 

@article{
author = "Ponjavić, Marijana and Nikolić, Marija S. and Nikodinović-Runić, Jasmina and Jeremić, Sanja and Stevanović, Sanja and Đonlagić, Jasna",
year = "2017",
abstract = "Short-term hydrolytic and enzymatic degradation of poly(epsilon-caprolactone) (PCL), one series of triblock (PCL/PEO/PCL) and the other of diblock (PCL/PEO) copolymers, with a low content of hydrophilic PEO segments is presented. The effect of the introduction of PEO as the central or lateral segment in the PCL chain on copolymer hydrolysis and biodegradation properties was investigated. FUR results revealed higher hydrolytic degradation susceptibility of diblock copolymers due to a higher hydrophilicity compared to PCL and triblock copolymers. Enzymatic degradation was tested using cell-free extracts of Pseudomonas aeruginosa PAO1, for two weeks by following the weight loss, changes in surface roughness, and changes in carbonyl and crystallinity index. The results confirmed that all samples underwent enzymatic degradation through surface erosion which was accompanied with a decrease in molecular weights. Diblock copolymers showed significantly higher weight loss and decrease in molecular weight in comparison to PCL itself and triblock copolymers. AFM analysis confirmed significant surface erosion and increase in RMS values. In addition, biodegradation of polymer films was tested in compost model system at 37 degrees C, where an effective degradation of block copolymers was observed.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Polymer Testing",
title = "Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions",
pages = "77-67",
volume = "57",
doi = "10.1016/j.polymertesting.2016.11.018"
}

Ponjavić, M., Nikolić, M. S., Nikodinović-Runić, J., Jeremić, S., Stevanović, S.,& Đonlagić, J.. (2017). Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions. in Polymer Testing
Elsevier Sci Ltd, Oxford., 57, 67-77.
https://doi.org/10.1016/j.polymertesting.2016.11.018

Ponjavić M, Nikolić MS, Nikodinović-Runić J, Jeremić S, Stevanović S, Đonlagić J. Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions. in Polymer Testing. 2017;57:67-77.
doi:10.1016/j.polymertesting.2016.11.018 .

Ponjavić, Marijana, Nikolić, Marija S., Nikodinović-Runić, Jasmina, Jeremić, Sanja, Stevanović, Sanja, Đonlagić, Jasna, "Degradation behaviour of PCL/PEO/PCL and PCL/PEO block copolymers under controlled hydrolytic, enzymatic and composting conditions" in Polymer Testing, 57 (2017):67-77,
https://doi.org/10.1016/j.polymertesting.2016.11.018 . .