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Effects of Chemotherapy for Metastatic Colorectal Cancer on the TGF-beta Signaling and Related miRNAs hsa-miR-17-5p, hsa-miR-21-5p and hsa-miR-93-5p
(Humana Press Inc, Totowa, 2021)
Metastatic colorectal cancer (mCRC) patients are treated with standard chemotherapeutic drugs in the form of FOLFOX and FOLFIRI regimens. There are no reliable markers that could predict response to chemotherapy for mCRC. ...
Silver(I) complexes with different pyridine-4,5-dicarboxylate ligands as efficient agents for the control of cow mastitis associated pathogens
(Royal Soc Chemistry, Cambridge, 2020)
Infections of the cow udder leading to mastitis and lower milk quality are one of the biggest problems in the dairy industry worldwide. Unfortunately, therapeutic options for the treatment of cow mastitis are limited as a ...
Antibiotic potential of the Ambigol Cyanobacterial natural product class and simplified synthetic analogs
(ACS Infectious DiseasesACS Infectious DiseasesACS Infect. Dis., 2023)
The ambigols are cyanobacterial natural products characterized by three polychlorinated aromatic building blocks connected by biaryl and biaryl ether bridges. All ambigols known to date possess promising biological activities. ...
Lung microbiota changes during pulmonary Aspergillus fumigatus infection in rats
(Microbes and InfectionMicrobes and InfectionMicrobes and Infection, 2023)
Since the realization that the lungs are not sterile but are normally inhabited by various bacterial species, studies have been conducted to define healthy lung microbiota and to investigate whether it changes during lung ...
Zinc(II) complexes with aromatic nitrogen-containing heterocycles as antifungal agents: Synergistic activity with clinically used drug nystatin
(Elsevier Science Inc, New York, 2020)
Three novel Zn(II) complexes, [ZnCl2(qz)(2)] (1), [ZnCl2(1,5-naph)](n) (2) and [ZnCl2(4,7-phen)(2)] (3), where qz is quinazoline, 1,5-naph is 1,5-naphthyridine and 4,7-phen is 4,7-phenanthroline, were synthesized by the ...
Complete mitogenome data for the Serbian population: the contribution to high-quality forensic databases
(New York : Springer, 2020)
Mitochondrial genome (mtDNA) is a valuable resource in resolving various human forensic casework. The usage of variability of complete mtDNA genomes increases their discriminatory power to the maximum and enables ultimate ...
Genotypes and virulence factors in Staphylococcus aureus isolated from dairy cows with subclinical mastitis in Serbia
(Comparative Immunology, Microbiology and Infectious DiseasesComparative Immunology, Microbiology and Infectious DiseasesComparative Immunology, Microbiology and Infectious Diseases, 2023)
This study aimed to determine the prevalence of Staphylococcus aureus subclinical mastitis and to genotype the S. aureus isolates using the 16S–23S rRNA intergenic spacer (RS-PCR) method. In addition, the genes responsible ...
Redesigned pMAL expression vector for easy and fast purification of active native antimicrobial peptides
(Wiley, Hoboken, 2022)
Aims The aim of this study was to construct the improved pMAL expression vector to increase the efficacy of purification of small native peptides and their clear-cut separation from MBP tag. The modifications we introduced ...
Quinolines and quinolones as antibacterial, antifungal, anti-virulence, antiviral and anti-parasitic agents
(Springer, 2020)
Infective diseases have become health threat of a global proportion due to appearance and spread of microorganisms resistant to majority of therapeutics currently used for their treatment. Therefore, there is a constant ...
Lectin from Laetiporus sulphureus effectively inhibits angiogenesis and tumor development in the zebrafish xenograft models of colorectal carcinoma and melanoma
(Elsevier, Amsterdam, 2020)
In spite of extensive usage of Laetiporus sulphureus (sulphur polypore) in traditional European and Asian ethnomedicine for centuries, its anticancer therapeutic potential and toxicity profile remained explored in animal ...