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Приказ резултата 11-20 од 314
Cardiac transcription factor Nkx2.5 interacts with p53 and modulates its activity
(Elsevier Science Inc, New York, 2015)
Transcription factor Nkx2.5, essential for heart development, regulates cardiomyocyte-specific gene expression through combinatorial interactions with other cardiac-restricted (GATA4 and dHAND) or ubiquitous (p300) ...
The overexpression of SOX2 affects the migration of human teratocarcinoma cell line NT2/D1
(Acad Brasileira De Ciencias, Rio Janeiro, 2015)
The altered expression of the SOX2 transcription factor is associated with oncogenic or tumor suppressor functions in human cancers. This factor regulates the migration and invasion of different cancer cells. In this study ...
Expression of bacteriocin LsbB is dependent on a transcription terminator
(Elsevier Gmbh, Urban & Fischer Verlag, Jena, 2015)
The production of LsbB, leaderless class II bacteriocin, is encoded by genes (lsbB and lmrB) located on plasmid pMN5 in Lactococcus lactis BGMN1-5. Heterologous expression of the lsbB gene using the pAZIL vector (pAZIL-lsbB) ...
Estradiol enhances effects of fructose rich diet on cardiac fatty acid transporter CD36 and triglycerides accumulation
(European Journal of Pharmacology, 2012)
Fructose rich diet increases hepatic triglycerides production and has deleterious cardiac effects. Estrogens are involved in regulation of lipid metabolism as well, but their effects are cardio beneficial. In order to study ...
The use of D-dimer with new cutoff can be useful in diagnosis of venous thromboembolism in pregnancy
(Elsevier, Amsterdam, 2010)
Objective: D-dimer testing has an important role in the exclusion of acute venous thromboembolism (VTE) in the nonpregnant population. Establishing D-dimers role in the diagnosis of VTE in pregnancy is hampered because of ...
The Spatiotemporal Segregation of GAD Forms Defines Distinct GABA Signaling Functions in the Developing Mouse Olfactory System and Provides Novel Insights into the Origin and Migration of GnRH Neurons
(Wiley, Hoboken, 2015)
Gamma-aminobutyric acid (GABA) has a dual role as an inhibitory neurotransmitter in the adult central nervous system (CNS) and as a signaling molecule exerting largely excitatory actions during development. The rate-limiting ...
The Role of Lymphocyte to Monocyte Ratio, Microvessel Density and HiGH CD44 Tumor Cell Expression in Non Hodgkin Lymphomas
(Springer, Dordrecht, 2016)
Prognostic significance of immune microenvironment has been emphasized using the most advanced analysis, with consecutive attempts to reveal prognostic impact of this findings. The aim of this study was to compare and ...
Emergence of VIM-2 metallo-beta-lactamase-producing Pseudomonas aeruginosa isolates in a paediatric hospital in Serbia
(Soc General Microbiology, Reading, 2011)
Molecular detection and surveillance of the
resistance genes harboured by
Pseudomonas aeruginosa are becoming
increasingly important in assessing and
controlling spread and colonization in
hospitals, and in guiding ...
Saquinavir-NO inhibits S6 kinase activity, impairs secretion of the encephalytogenic cytokines interleukin-17 and interferon-gamma and ameliorates experimental autoimmune encephalomyelitis
(Elsevier Science Bv, Amsterdam, 2013)
NO-hybridization of the HIV protease inhibitor Saquinavir generates a new chemical entity named Saq-NO, that retains the anti-viral activity and exerts lower toxicity. We show that Saq-NO inhibited the generation of various ...
Early growth response protein 1 acts as an activator of SOX18 promoter
(Nature Publishing Group, New York, 2010)
Sex-determining region Y box 18 (Sox18/SOX18) gene is an important regulator of vascular development playing a role in endothelial cell specification or differentiation, angiogenesis and atherogenesis. The aim of this study ...