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Mineral waters of Serbia and development of phototrophic microbial communities near points of emergence and on wellheads
(Karst Research Inst Zrc Sazu, Postojna, 2017)
Phototropic microorganisms in thermal mats had not attracted enough attention in Serbia in the past. The research presented in this paper is the first to address biofilms at selected occurrences of mineral water in Serbia ...
Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel
(MDPI, Basel, 2018)
P2X2 receptors (P2X2R) exhibit a slow desensitization during the initial ATP application and a progressive, calcium-dependent increase in rates of desensitization during repetitive stimulation. This pattern is observed in ...
Ugt1a1 (ta)(n) promoter genotype: diagnostic and population pharmacogenetic marker in Serbia
(Macedonian Acad Sciences Arts, Skopje, 2018)
The UGT1A1 enzyme is involved in the metabolism of bilirubin and numerous medications. Unconjugated hyper-bilirubinemia, commonly presented as Gilbert syndrome (GS), is a result of decreased activity of the UGT1A1 enzyme, ...
Formation of silica aggregates in sorghum root endodermis is predetermined by cell wall architecture and development
(Oxford Univ Press, Oxford, 2017)
Background and Aims Deposition of silica in plant cell walls improves their mechanical properties and helps plants to withstand various stress conditions. Its mechanism is still not understood and silica-cell wall interactions ...
Differences in bioactivity of three endemic Nepeta species arising from main terpenoid and phenolic constituents
(Srpsko biološko društvo, Beograd, i dr., 2018)
Methanol extracts of three endemic Nepeta species were analyzed for their main secondary metabolites, terpenes and phenolics, and further investigated for antioxidant capacity and embryonic toxicity in zebrafish. UHPLC/DAD/(+/-) ...
Physiological and cell ultrastructure disturbances in wheat seedlings generated by Chenopodium murale hairy root exudate
(Springer Wien, Wien, 2018)
Chenopodium murale L. is an invasive weed species significantly interfering with wheat crop. However, the complete nature of its allelopathic influence on crops is not yet fully understood. In the present study, the focus ...
Alpha-1-Antitrypsin Antagonizes Cisplatin-Induced Cytotoxicity in Prostate Cancer (PC3) and Melanoma Cancer (A375) Cell Lines
(Springer, Dordrecht, 2017)
Increased circulating alpha-1-antitrypsin (AAT) correlates with cancer stage/aggressiveness, but its role in cancer biology is unclear. We revealed antagonistic effect of AAT to cisplatin-induced cytotoxicity in prostate ...
Fingerprinting of the antioxidant status in Alyssum markgrafii shoots during nickel hyperaccumulation in vitro
(Springer Heidelberg, Heidelberg, 2018)
This study investigated the role of antioxidant system of Alyssum markgrafii, during long-term exposure to 0.5 or 1 mM NiCl2 x 6H(2)O in vitro. Applied methodology included sample preparation protocol which reduces oxidation ...
Can untreated PKU patients escape from intellectual disability? A systematic review
(BMC, London, 2018)
Background: Phenylketonuria (PKU) is often considered as the classical example of a genetic disorder in which severe symptoms can nowadays successfully be prevented by early diagnosis and treatment. In contrast, untreated ...
Structure and function of PspA and Vipp1 N-terminal peptides: Insights into the membrane stress sensing and mitigation
(Elsevier Science Bv, Amsterdam, 2017)
The phage shock protein (Psp) response maintains integrity of the inner membrane (IM) in response to extracytoplasmic stress conditions and is widely distributed amongst enterobacteria. Its central component PspA, a member ...