Претраживање
Приказ резултата 1-10 од 436
Untreated PKU patients without intellectual disability: SHANK gene family as a candidate modifier
(Elsevier, Amsterdam, 2021)
Phenylketonuria (PKU) is an inborn error of metabolism caused by variants in the phenylalanine hydroxylase (PAH) gene and it is characterized by excessively high levels of phenylalanine in body fluids. PKU is a paradigm ...
The influence of Wilms' tumor 1 gene expression level on prognosis and risk stratification of acute promyelocytic leukemia patients
(Wiley, Hoboken, 2020)
Introduction Patients with acute promyelocytic leukemia (APL) are characterized by the highest expression of Wilms' tumor 1 (WT1) gene compared with other subtypes of acute myeloid leukemia, and yet this molecular marker ...
Importance of pharmacogenetic markers in the methylenetetrahydrofolate reductase gene during methotrexate treatment in pediatric patients with acute lymphoblastic leukemia
(Srpsko biološko društvo, Beograd, i dr., 2017)
Despite remarkable progress in survival of children with acute lymphoblastic leukemia (ALL) which has reached about 85%, early toxicity and relapse rate remain issues that need to to be resolved. Genetic variants are ...
Transport of silver nanoparticles from nanocomposite Ag/alginate hydrogels under conditions mimicking tissue implantation
(Savez hemijskih inženjera, Beograd, 2017)
The aim of this work was to assess phenomena occurring during AgNP transport from nanocomposite Ag/alginate hydrogels under conditions relevant for potential biomedical applications as antimicrobial soft tissue implants. ...
Optimization of ultrasound-assisted extraction of total polyphenolic compounds from Juglans nigra L. leaves
(Srpsko hemijsko društvo, Beograd, 2018)
The ultrasound-assisted extraction of Juglans nigra L. leaves was optimized with respect to total phenolic content (TP) of the extracts by varying the concentration of aqueous ethanol solution (E) and different solvent-to-solid ...
Early onset of abdominal venous thrombosis in a newborn with homozygous type II heparin-binding site antithrombin deficiency
(Lippincott Williams & Wilkins, Philadelphia, 2017)
The overall incidence of thromboembolic events in the neonatal period is 5 per 100 000 births, wherein more than 40% of all such manifestations are symptomatic renal vein thromboses. We describe the case of a newborn female ...
Ugt1a1 (ta)(n) promoter genotype: diagnostic and population pharmacogenetic marker in Serbia
(Macedonian Acad Sciences Arts, Skopje, 2018)
The UGT1A1 enzyme is involved in the metabolism of bilirubin and numerous medications. Unconjugated hyper-bilirubinemia, commonly presented as Gilbert syndrome (GS), is a result of decreased activity of the UGT1A1 enzyme, ...
Mineral waters of Serbia and development of phototrophic microbial communities near points of emergence and on wellheads
(Karst Research Inst Zrc Sazu, Postojna, 2017)
Phototropic microorganisms in thermal mats had not attracted enough attention in Serbia in the past. The research presented in this paper is the first to address biofilms at selected occurrences of mineral water in Serbia ...
Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii growth and anti-cancer molecules
(Srpsko hemijsko društvo, Beograd, 2015)
New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for their antimalarial activity against chloroquine resistant and susceptible Plasmodium falciparum strains. ...
Screening of alpha-1-antitrypsin gene by denaturing gradient gel electrophoresis (DGGE)
(Elsevier, Amsterdam, 2006)
Alpha-1-antitrypsin (AAT) is a serine protease inhibitor whose deficiency could cause emphysema and liver disease and, as recently described, could be a risk factor for lung cancer development. Alpha-1-antitrypsin inhibits ...