Претраживање
Приказ резултата 1-10 од 20
Ekspresija Bcl2 gena kod pacijenata sa hroničnom limfocitnom leukemijom / Expression of the Bcl2 gene in chronic lymphocytic leukaemia patients
(Univerzitet u Kragujevcu - Fakultet medicinskih nauka, Kragujevac, 2015)
Hronična limfocitna leukemija (HLL) se manifestuje kao klonska ekspanzija zrelih B limfocita, čija se akumulacija pripisuje prvenstveno poremećajima procesa apoptoze. U HLL su uočene genetičke promene i aberantna ekspresija ...
Multiple antimelanoma potential of dry olive leaf extract
(Wiley, Hoboken, 2011)
Various constituents of the olive tree (Olea europaea) have been traditionally used in the treatment of infection, inflammation, prevention of chronic diseases, cardiovascular disorders and cancer. The anticancer potential ...
ALPHA-1 Antitrypsin Affects U0126-Induced Cytotoxicity in Colon Cancer Cell Line (HCT116)
(Maik Nauka/Interperiodica/Springer, New York, 2016)
Alpha-1-antitrypsin (AAT), an acute phase protein, is the principal circulatory anti-protease. This multifunctional protein is encoded by the SERPINA1 gene. Although AAT was recognised as a potential tumour marker, its ...
The Role of Autophagy and Apoptosis in Affected Skin and Lungs in Patients with Systemic Sclerosis
(MDPI, 2023)
Systemic sclerosis (SSc) is a complex autoimmune inflammatory disorder with multiple organ involvement. Skin changes present the hallmark of SSc and coincide with poor prognosis. Interstitial lung diseases (ILD) are the ...
Macrophage migration inhibitory factor (MIF) enhances palmitic acid-and glucose-induced murine beta cell dysfunction and destruction in vitro
(Taylor & Francis Ltd, Abingdon, 2012)
Although several reports suggest a potentially deleterious role of macrophage migration inhibitory factor (MIF) in type 2 diabetes (T2D) pathology, it is still unclear how this pro-inflammatory cytokine acts on pancreatic ...
In vitro and in vivo anticancer action of Saquinavir-NO, a novel nitric oxide-derivative of the protease inhibitor saquinavir, on hormone resistant prostate cancer cells
(Taylor & Francis Inc, Philadelphia, 2011)
The NO-derivative of the HIV protease inhibitor saquinavir (Saq-NO) is a nontoxic variant of the parental drug with enhanced anticancer activity on several cell lines. However, it is still unclear whether the p53 status ...
New polyene macrolide family produced by submerged culture of Streptomyces durmitorensis
(Nature Publishing Group, London, 2011)
A new polyene macrolide family, closely related to the pentaene macrolide antibiotic roflamycoin, was isolated from the both fermentation broth and biomass of Streptomyces durmitorensis wild-type strain MS405. The main ...
Udruženost ekspresije Bax gena i Bcl2/Bax odnosa sa kliničkim i molekularnim prognostičkim markerima u hroničnoj limfocitnoj leukemiji / Association of Bax expression and Bcl2/Bax ratio with clinical and molecular prognostic markers in chronic lymphocytic leukemia
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2016)
Uvod: Rezistencija na apoptozu koja karakteriše maligne B limfocite in vivo u hroničnoj limfocitnoj leukemiji (HLL) delimično je uzrokovana unutrašnjim poremecajima apoptotske mašinerije u ovim celijama. Ti poremecaji su ...
An updated pharmacological insight into calotropin as a potential therapeutic agent in cancer
(Frontiers in Pharmacology, 2023)
Calotropin is a pharmacologically active compound isolated from milkweed plants like Calotropis procera, Calotropis gigantea, and Asclepias currasavica that belong to the Asclepiadaceae family. All of these plants are ...
Numerical and Biological Modeling Approach in the Analysis of the Cancer Viability and Apoptosis
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Biomedicine is a multidisciplinary branch of science that requires a clear approach to the
study and analysis of various life processes necessary for a deeper understanding of
human health. This research focuses on the ...