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Three lines of evidence of the hepatotoxicity young researchers of a mixture containing phthalates and bisphenol a: in silico and two in vivo models
(Beograd : Udruženje toksikologa Srbije, 2023)
The extensive usage of bis(2-ethylhexyl) phthalate (DEHP), dibutyl phthalate (DBP), and bisphenol A
(BPA) creates a lot of opportunities for combined human exposure to these hazardous compounds in
everyday life and a ...
E-cigarette liquid and condensate leads to impaired embryonic development of zebrafish
(Institute of Molecular Genetics and Genetic Engineering (IMGGE), University of Belgrade, 2023)
Introduction: E-cigarettes are advertised as safer alternative to tradicional cigarettes. However, they
contain chemicals that can exhibit toxic effects on the organism. Notably, effects of e-cigarettes on in
utero ...
Novel Quorum Quenching YtnP Lactonase From Bacillus paralicheniformis Reduces Pseudomonas aeruginosa Virulence and Increases Antibiotic Efficacy in vivo
(Frontiers Media Sa, Lausanne, 2022)
Bacterial infections have become increasingly difficult to treat due to the occurrence of antibiotic-resistant strains. A promising strategy to increase the efficacy of therapy is to combine antibacterials with agents that ...
Anti-Virulence Potential and In Vivo Toxicity of Persicaria maculosa and Bistorta officinalis Extracts
(MDPI, Basel, 2020)
Many traditional remedies represent potential candidates for integration with modern medical practice, but credible data on their activities are often scarce. For the first time, the anti-virulence potential and the safety ...
Streptomyces sp. BV410 isolate from chamomile rhizosphere soil efficiently produces staurosporine with antifungal and antiangiogenic properties
(Wiley, Hoboken, 2020)
Applying a bioactivity-guided isolation approach, staurosporine was separated and identified as the active principle in the culture extract of the new isolate Streptomyces sp. BV410 collected from the chamomile rhizosphere. ...
A Comprehensive Evaluation of Sdox, a Promising H2S-Releasing Doxorubicin for the Treatment of Chemoresistant Tumors
(Frontiers Media Sa, Lausanne, 2022)
Sdox is a hydrogen sulfide (H2S)-releasing doxorubicin effective in P-glycoprotein-overexpressing/doxorubicin-resistant tumor models and not cytotoxic, as the parental drug, in H9c2 cardiomyocytes. The aim of this study ...
Polyenes in Medium Chain Length Polyhydroxyalkanoate (mcl-PHA) Biopolymer Microspheres with Reduced Toxicity and Improved Therapeutic Effect against Candida Infection in Zebrafish Model
(MDPI, Basel, 2022)
Immobilizing antifungal polyenes such as nystatin (Nys) and amphotericin B (AmB) into biodegradable formulations is advantageous compared to free drug administration providing sustained release, reduced dosing due to ...
Karakterizacija gena ankrd1a, ankrd1b i ankrd2 zebrice (Danio rerio) u razviću i odgovoru na stres / Characterization of zebrafish ankrd1a, ankrd1b and ankrd2 genes in development and stress response
(Univerzitet u Beogradu, Biološki fakultet, 2021)
U popriječno-prugastim mišićima članovi familije mišićnih proteina sa ankirinskim ponovcima (eng. Muscle Ankyrin Repeat Proteins, MARP) učestvuju u mehanotransdukciji signala sa sarkomere u jedro, gdje modulišu ekspresiju ...
Synthesis, Anticancer Potential and Comprehensive Toxicity Studies of Novel Brominated Derivatives of Bacterial Biopigment Prodigiosin from Serratia marcescens ATCC 27117
(MDPI, Basel, 2022)
Prodigiosins (prodiginines) are a class of bacterial secondary metabolites with remarkable biological activities and color. In this study, optimized production, purification, and characterization of prodigiosin (PG) from ...
Exploring zebrafish swim bladder as a model for chronic lung diseases
(National Institute of Genetics, Mishima, Japan, 2023)
This project aims to identify transgenic zebrafish lines within the Kawakami Laboratory collection,
exhibiting Gal4 expression patterns in the swim bladder, to establish a robust model for investigating
the impacts of ...