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Persistence of plasmids targeted by CRISPR interference in bacterial populations
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
CRISPR-Cas systems provide prokaryotes with an RNA-guided defense against foreign
mobile genetic elements (MGEs) such as plasmids and viruses. A common mechanism by
which MGEs avoid interference by CRISPR consists of ...
Pangenomic Alignment: Strings plus Graphs
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
The use of only one or a few reference genomes for DNA alignment is known to bias
research results and medical diagnoses, but aligning against many reference genomes
has been problematic. If we represent such a pangenomic ...
Circular Codes in the Genetic Information
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Codes are the sets of words over arbitrary alphabets with the property of unique
decipherability.
Circular codes are a special class of codes. They are the sets of words with the property
of unique recognition of the ...
Exploring Changes in Diagnoses during the COVID-19 Era: Comparative Analysis
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
The healthcare sector is just one of several areas of society that have been significantly impacted
by the COVID-19 pandemic. This paper aims to analyze the changes observed in the medical
profession’s approach to ...
Some Applications of Graph-Based Machine Learning Methods on Biological Data
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Machine learning has made considerable contributions to various fields, most notably by
providing methods for predictive modeling and data analysis. Usually, different kinds of
data are best modeled by specialized machine ...
Genomic Surveillance and Phylogenetic Analysis of SARS-CoV-2 Variants in Serbia: Insights into Evolutionary Dynamics and Genetic Diversity
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic, resulting in significant morbidity and mortality worldwide. Understanding the evolutionary
dynamics and genetic diversity of ...
Pathway analysis of CD8+ T cell transcriptome in glioblastoma patients reveales multiple sclerosis signaling pathway as the top rated upregulated disease pathway in tumor infiltrating cells
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
The significance of CD8+ T cell central nervous system migration and activation in the
progression of glioblastoma is well documented. However, molecular signaling pathways
regulation related to migration and activation ...
Analysis of nucleotide sequence repeats in coronaviruses
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Repeats in nucleotide sequences are connected with various genome characteristics.
RNA secondary structures are related to repeats at the primary structure level. Four
different types of nucleotide repeats may be identified: ...
Numerical and Biological Modeling Approach in the Analysis of the Cancer Viability and Apoptosis
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Biomedicine is a multidisciplinary branch of science that requires a clear approach to the
study and analysis of various life processes necessary for a deeper understanding of
human health. This research focuses on the ...
Genetic Complexity and Synteny Analysis of Castanea Genomes: Unveiling the Significance of Chestnut Species in Ecological and Genomic Perspectives
(Belgrade : Institute of molecular genetics and genetic engineering, 2023)
Castanea, a prominent genus within the Fagaceae family, thrives across the expansive
woodlands of eastern North America, Europe, and Asia, holding considerable ecological
and economic significance. Among the invaluable ...